The Safety and Efficacy of Aspirin Discontinuation on a Background of a P2Y12 Inhibitor in Patients After Percutaneous Coronary Intervention: A Systematic Review …

ML O'Donoghue, SA Murphy, MS Sabatine - Circulation, 2020 - Am Heart Assoc
… with aspirin and a P2Y 12 inhibitor has been shown to reduce the risk of major adverse
cardiovascular events (MACE) compared with aspirin aloneaspirin in favor of P2Y 12 inhibitor

P2Y12 inhibitors plus aspirin versus aspirin alone in patients with minor stroke or high-risk transient ischemic attack

ZX Li, Y Xiong, HQ Gu, M Fisher, Y Xian, SC Johnston… - Stroke, 2021 - Am Heart Assoc
Background and purpose: We performed a systemic review and meta-analysis to elucidate
the effectiveness and safety of dual antiplatelet (DAPT) therapy with P2Y12 inhibitors (…

Monotherapy with a P2Y12 inhibitor or aspirin for secondary prevention in patients with established atherosclerosis: a systematic review and meta-analysis

M Chiarito, J Sanz-Sánchez, F Cannata, D Cao… - The Lancet, 2020 - thelancet.com
… 1 year after randomisation, when patients continued to be treated with ticagrelor alone or
aspirin alone. All analyses were performed according to the intention-to-treat principle. The two-…

P2Y12 inhibitor versus aspirin monotherapy for secondary prevention of cardiovascular events: meta-analysis of randomized trials

D Aggarwal, K Bhatia, ZS Chunawala… - … heart journal open, 2022 - academic.oup.com
… to compare P2Y12 inhibitor monotherapy versus aspirin … Monotherapy with P2Y12 inhibitors
(clopidogrel or ticagrelor) … 0.92, I2 = 0%) compared with aspirin monotherapy. There was no …

Novel approaches to P2Y12 inhibition and aspirin dosing

WAE Parker, RF Storey - Platelets, 2021 - Taylor & Francis
… benefit of ticagrelor in those who had received aspirin in the … with aspirin and ticagrelor
may be superior to aspirin alone, … attack treated with ticagreLor and aspirin for prEvention of …

P2Y12 Inhibitor or Aspirin Monotherapy for Secondary Prevention of Coronary Events

F Gragnano, D Cao, L Pirondini, A Franzone… - Journal of the American …, 2023 - jacc.org
… 12 inhibitor monotherapy vs aspirin in patients with CAD. … P2Y 12 inhibitors (clopidogrel,
prasugrel, or ticagrelor) vs aspirin … of P2Y 12 inhibitor monotherapy vs aspirin monotherapy after …

P2Y12 inhibitor monotherapy versus aspirin monotherapy after short-term dual antiplatelet therapy for percutaneous coronary intervention: Insights from a network …

T Kuno, H Ueyama, H Takagi, S Bangalore - American heart journal, 2020 - Elsevier
… Second, although we compared aspirin versus P 2 Y 12 inhibitor, the P 2 Y 12 inhibitor
evaluated varied (clopidogrel vs ticagrelor), and there were insufficient data to further evaluate …

P2Y12 Inhibitor or Aspirin Following Dual Antiplatelet Therapy After Percutaneous Coronary Intervention: A Network Meta-Analysis

G Andò, GA De Santis, A Greco, L Pistelli… - Cardiovascular …, 2022 - jacc.org
… The aim of this study was to compare aspirin vs P2Y 12 inhibitor (P2Y 12 -I) monotherapy
after dual antiplatelet therapy (DAPT) discontinuation in patients undergoing percutaneous …

P2Y12 inhibitor monotherapy or dual antiplatelet therapy after coronary revascularisation: individual patient level meta-analysis of randomised controlled trials

M Valgimigli, F Gragnano, M Branca, A Franzone… - Bmj, 2021 - bmj.com
… therapy (DAPT), consisting of aspirin and an oral P2Y12 inhibitor, mitigates the incidence
of … compared with aspirin alone.A few studies have assessed oral P2Y12 inhibitor monotherapy …

Anticoagulants (Thrombin Inhibitors) and Aspirin Synergize With P2Y12 Receptor Antagonism in Thrombosis

P André, T LaRocca, SM Delaney, PH Lin, D Vincent… - Circulation, 2003 - Am Heart Assoc
… mice were administered aspirin or coagulation inhibitors (C921… that (1) thrombin inhibitors
and aspirin have a demonstrable … in vivo by the inclusion of aspirin and/or a thrombin inhibitor. …