[HTML][HTML] In the presence of strong P2Y12 receptor blockade, aspirin provides little additional inhibition of platelet aggregation

PCJ Armstrong, PD Leadbeater, MV Chan… - Journal of Thrombosis …, 2011 - Elsevier
… the effects of PAM and aspirin. Aspirin (30 μmol L −1 ) alone caused complete inhibition
of the production of TXA 2 in response to AA (Fig. 3A), collagen (Fig. 3B) and epinephrine (Fig. …

Are P2Y12 inhibitors superior to aspirin for long-term secondary prevention of cardiovascular disease?

S Carlin, J Eikelboom - Expert Review of Cardiovascular Therapy, 2023 - Taylor & Francis
… of aspirin in these populations found a 20% reduction in CV events [Citation1]. Clopidogrel
was the first P2Y12 inhibitor to be evaluated as an alternative to aspirin … that P2Y12 inhibitors

Laboratory monitoring of P2Y12 inhibitors: communication from the SSC of the ISTH

AL Frelinger, C Gachet, AD Mumford, P Noris… - Journal of Thrombosis …, 2018 - jthjournal.org
… Dual antiplatelet therapy (DAPT) with aspirin and a P2Y 12 platelet adenosine diphosphate
(ADP) … Effects of pretreatment with clopidogrel and aspirin followed by long‐term therapy in …

Triple antithrombotic therapy with aspirin, P2Y12 inhibitor, and warfarin after percutaneous coronary intervention: an evaluation of prasugrel or ticagrelor versus …

NJ Verlinden, JC Coons, CJ Iasella… - Journal of …, 2017 - journals.sagepub.com
… a P2Y12 inhibitor or DAPT (1-12 months) compared to a VKA plus DAPT (1-12 months).
However, the use of prasugrel and ticagrelor … with using newer oral P2Y12 inhibitors as part of …

P2y12 inhibitor monotherapy versus conventional dual antiplatelet therapy or aspirin monotherapy in acute coronary syndrome: a pooled analysis of the SMART …

PS Song, YH Park, JH Oh, YB Song, SH Choi… - The American Journal of …, 2021 - Elsevier
P2Y12 inhibitor monotherapy compared with conventional dual antiplatelet therapy (DAPT)
and aspirin … categorized as P2Y12 inhibitor monotherapy (P2Y12 inhibitor monotherapy after …

Pre-treatment with P2Y12 inhibitors in ACS patients: who, when, why, and which agent?

D Sibbing, A Kastrati, PB Berger - European heart journal, 2016 - academic.oup.com
… with an irreversible mode of action, received approval in 1997 following the CAPRIE trial, a
randomized comparison of clopidogrel alone vs. aspirin alone in patients with atherosclerotic …

Dual antiplatelet therapy in cardiovascular disease: does aspirin increase clinical risk in the presence of potent P2Y12 receptor antagonists?

TD Warner, PCJ Armstrong, NP Curzen, JA Mitchell - Heart, 2010 - heart.bmj.com
… To summarise our hypothesis, when aspirin is used alone as an antithrombotic agent in
high-risk patients, its potentially deleterious cardiovascular effects are more than balanced by its …

Meta-analysis of dual antiplatelet therapy versus monotherapy with P2Y12 inhibitors in patients after percutaneous coronary intervention

AH Malik, S Yandrapalli, SS Shetty, WS Aronow… - The American Journal of …, 2020 - Elsevier
… DAPT followed by monotherapy with aspirin alone with long-term DAPT … aspirin monotherapy
after 3 months of DAPT especially in patients presenting with ACS. As P2Y12 inhibitors

[HTML][HTML] Aspirin-free antiplatelet regimens after PCI: when is it best to stop aspirin and who could ultimately benefit?

M Tomaniak, RF Storey… - EuroIntervention, 2020 - eurointervention.pcronline.com
… comparison between ticagrelor and aspirin from 12 … ticagrelor alone or ticagrelor and aspirin
according to the GLOBAL LEADERS protocol13. Continuation of aspirin on top of ticagrelor

Switching from dual antiplatelet therapy with aspirin plus a P2Y12 inhibitor to dual pathway inhibition with aspirin plus vascular-dose rivaroxaban: the Switching Anti …

L Ortega-Paz, F Franchi, F Rollini… - Thrombosis and …, 2024 - thieme-connect.com
… ) with aspirin plus a P2Y12 inhibitor or dual pathway inhibition (DPI) with aspirin plus a …
) trial showing that, compared to aspirin alone, DPI was more effective in preventing ischemic …