Controlled release of heparin from poly (ε-caprolactone) electrospun fibers

E Luong-Van, L Grøndahl, KN Chua, KW Leong… - Biomaterials, 2006 - Elsevier
… poly(ε-caprolactone) (PCL) fiber mats for assessment as a … Assessment of drug loading,
and imaging of fluorescently … the encapsulated heparin was released by diffusional control …

[HTML][HTML] Assessment of the release of vascular endothelial growth factor from 3D-printed poly-ε-caprolactone/hydroxyapatite/calcium sulfate scaffold with enhanced …

CY Chen, CC Chen, CY Wang, AKX Lee, CL Yeh… - Polymers, 2020 - mdpi.com
Vascular endothelial growth factor (VEGF) is one of the most crucial growth factors and an
assistant for the adjustment of bone regeneration. In this study, a 3D scaffold is fabricated …

[HTML][HTML] Assessment of the release profile of fibroblast growth factor-2-load mesoporous calcium silicate/poly-ε-caprolactone 3D scaffold for regulate bone …

CT Kao, YJ Chen, TH Huang, YH Lin, TT Hsu, CC Ho - Processes, 2020 - mdpi.com
… Although the extremely slow degradation rate of PCL could completely impede the release
of FGF-2 from the scaffolds, our results indicate that sustained release of FGF-2 from the …

Development and biocompatibility assessments of poly (3-hydroxybutyrate-co-ε-caprolactone) microparticles for diclofenac sodium delivery

T Musumeci, A Bonaccorso, C Carbone… - Journal of Drug Delivery …, 2020 - Elsevier
… We then studied the release of DFNa by the MPs and assessed the kinetic profile by applying
different mathematical models. The most promising MPs formulation and the copolymer as …

Primidone-loaded poly-ε-caprolactone nanocapsules: incorporation efficiency and in vitro release profiles

V Ferranti, H Marchais, C Chabenat… - International journal of …, 1999 - Elsevier
… The aim of this study was to prepare nanocapsules of poly-ε-caprolactone containing …
encapsulation efficiency) were evaluated and the in vitro release profiles were assessed. …

Release of bioactive human growth hormone from a biodegradable material: Poly (ϵcaprolactone)

CJ Goodwin, M Braden, S Downes… - Journal of Biomedical …, 1998 - Wiley Online Library
… A similar study in which hormone-loaded discs of PCL had been stored at −20C for the
same time intervals showed no decline in hormone release when assessed by either bio- or …

Functionalized Hydrophobic Poly(glycerol-co-ε-caprolactone) Depots for Controlled Drug Release

JB Wolinsky, ST Yohe, YL Colson… - …, 2012 - ACS Publications
… The release kinetics from HCPT-loaded films were assessed in PBS buffer at 37 C. Specifically,
films comprised of 5 mg polymer and 100 μg HCPT were cast onto glass coverslips and …

[HTML][HTML] Characterization and in vitro and in vivo evaluation of tacrolimus-loaded poly (ε-caprolactone) nanocapsules for the management of atopic dermatitis

GA Camargo, L Ferreira, DJ Schebelski, AM Lyra… - Pharmaceutics, 2021 - mdpi.com
… Therefore, this study aimed to prepare, characterize, and evaluate the in vitro drug release
… Statistical significance between groups was assessed by ANOVA, followed by Tukey’s post-…

A poly (ε-caprolactone) device for sustained release of an anti-glaucoma drug

MV Natu, MN Gaspar, CAF Ribeiro, IJ Correia… - Biomedical …, 2011 - iopscience.iop.org
release. Nonlinear regression analysis suggested that a degradation model fully describes
the release curve considering a triphasic release … cytotoxicity assessment using the MTT test. …

In vitro biocompatibility assessment of poly (ε-caprolactone) films using L929 mouse fibroblasts

MC Serrano, R Pagani, M Vallet-Regı, J Pena… - Biomaterials, 2004 - Elsevier
… In the present study cell adhesion, proliferation, morphology, mitochondrial function and
LDH release were analyzed after the culture of L929 cells on PCL membranes with smooth and …