… the adipose tissue environment, while highlighting its heterogeneity. Finally, we detail how
obesity … both adipose tissue and local macrophage populations. Understanding macrophage …

… about adipose tissue macrophage (ATM) biology in the setting of obesity and metabolic disease
in a … Obesity-driven changes in adipose tissue-associated macrophages (ATMs). In lean …

… , there is clear evidence that AT-infiltrating macrophages (ATMs) play a significant role in the
… discuss macrophage biology and pathophysiology in obesity-associated disease settings, …

… associated inflammation is characterized by an increased abundance of macrophages in
adipose tissue … underlying the recruitment of macrophages to adipose tissue and the insulin …

… adipose tissue macrophages but also elucidate the relationship between ATMs and human
diseases. … Figure 3 Related mechanisms of adipose tissue macrophages and type2 diabetes …

… on macrophage metabolism linked to functional phenotypes with an emphasis on macrophage
polarization in adipose tissue … roles of ATMs in adipose tissue can potentially provide …

… adipose tissue macrophages, and discuss their functions both in health and metabolic
diseases, including thermogenesis, obesity, insulin resistance as well as adipose tissue fibrosis. …

… in the adipose tissue can be referred to as “adipose tissue … , infiltration of macrophages in
the adipose tissue precedes … crucial for obesity-related adipose tissue inflammation. We have …

… conditions. Both conventional and tissue-specific functions of adipose tissue macrophages
(ATMs) in lean and obese adipose tissue are discussed and linked with metabolic and …

… related metabolic diseases. Here, we review the current literature on adipose tissue
macrophages … of these cells during obesity in adipose tissue. We discuss the fundamental roles of …