… The most important finding in the present study is that HTLV-I proviral DNA was frequently
d.etected in CNS tissue obtained at autopsy from patients with HAM/TSP. Interestingly, HAM/…

… ) proviral DNA in peripheral blood mononuclear cells from 18 patients with HTLV-I-associated …
HTLV-I carriers without HTLV-I-associated myelopathy/tropical spastic paraparesis, with or …

… -I-associated myelopathy/tropical spastic paraparesis (HAM/TSP) we investigated the dynamics
of HTLV-I proviral DNA … The estimation of the amount of HTLV-I proviral DNA was carried …

… HTLV-I-associated myelopathy/tropical … I proviral DNA load than healthy HTLV-I carriers (P
= 0.005, one-way Mann-Whitney test). As observed in other persistent infections, proviral DNA …

… DNA to avoid differences in the amount of amplified DNA caused by exponential growth (Kubota
et al., 1993). In this article, we estimated HTLV-I proviral DNA … of proviral DNA and the …

… –associated myelopathy with evidence of proviral DNA within spinal cord biopsy specimens,
13 the incidence of myelopathy in … developing HTLV-associated myelopathy/tropical spastic …

… HTLV-I proviral DNA could be detected in DNA extracted from affected spinal cords in HAM/…
) to determine which cells harbor the HTLV-I provirus in vivo in the spinal lesions of HAM/TSP…

The nucleotide sequence of human T‐lymphotropic virus type I (HTLV‐I) in central nervous
system tissue was determined in 3 autopsy cases with HTLV‐I–associated myelopathy (HAM)…

… type 1(HTLV-1)-associated myelopathy (HAM)/tropical spastic … proviral DNA amounts were
well correlated with the numbers of infiltrated CD4+ cells. In situ PCR of HTLV-1 proviral DNA …

… To determine how efficiently HTLV-I was replicating in HAM patients, patients diagnosed
as having typical HAM were tested for HTLV-I proviral DNA. The levels of proviral DNA …