… senescence and the senescent phenotype. Herein we review the molecular mechanisms
that underlie cellular senescence and the senescence associated … hypersecretory phenotype …

… analysis of cellular senescence and senescence-associated secretory phenotype (SASP) in
CKD is … the CKD-associated secretory phenotype and SASP, as detailed in Table ​1 below. …

… It is commonly believed to underlie organismal aging and age-associated diseases.
However, the mechanism by which cellular senescence contributes to aging and age-associated …

… Cellular senescence and the senescence-associated secretory phenotype (SASP) have …
This review first discusses the relationships among cellular senescence, the SASP and renal …

… fundamental aging mechanisms. One such mechanism is cellular senescence, which
can cause chronic inflammation through the senescence-associated secretory phenotype (SASP). …

… investigators are now revisiting senescence-associated secretory proteins in the context of
SASP, and these studies have broadened our view of cellular senescence. Functioning only …

… age-associated chronic inflammation, cellular senescence, and the senescence-associated
secretory phenotype (… We will consider links between cellular senescence and age-related …

… to showcase cellular senescence with relevance to COPD and the striking similarities
between the mediators and secretory phenotype in COPD and SASP. Keywords: senescence; …

… Several SASP components not only get secreted in the extracellular milieu, but also accumulate
at very high levels in cells undergoing cellular senescence. Among these components, …

… A fundamental feature of cellular senescence is the emergence of the Senescence-Associated
Secretory Phenotype (SASP), which represents a considerable source of inflammatory …