Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

…, Genetic Investigation of ANthropometric Traits (GIANT) … - … genetics, 2012 - nature.com
… To extend understanding of the genetic architecture and molecular basis of type 2 diabetes
(T2D), we conducted a meta-analysis of genetic variants on the Metabochip, including …

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes mellitus

NN Mehta - Circulation: Cardiovascular Genetics, 2012 - Am Heart Assoc
… -wide association (GWA) approaches have identified 56 genetic … understanding of the genetic
architecture and molecular … meta-analysis (34 840 cases and 114 981 controls) of genetic

Genetic architecture of wood properties based on association analysis and co‐expression networks in white spruce

M Lamara, E Raherison, P Lenz, J Beaulieu… - New …, 2016 - Wiley Online Library
… Our aim was to delineate the genetic architecture of wood traits in white spruce (Picea
glauca (Moench) Voss) by testing a large panel of genes with diverse functions and expression …

Genome-wide association analysis reveals insights into the genetic architecture of right ventricular structure and function

N Aung, JD Vargas, C Yang, K Fung, MM Sanghvi… - … genetics, 2022 - nature.com
… in our understanding of the genetic architecture of RV phenotypes in the general population
and provide a foundation to characterize the genetic drivers of RV remodeling in the future. …

[HTML][HTML] Genome-wide association analysis of psoriatic arthritis and cutaneous psoriasis reveals differences in their genetic architecture

PE Stuart, RP Nair, LC Tsoi, T Tejasvi, S Das… - … of Human Genetics, 2015 - cell.com
… To discern differences in genetic risk factors for PsA and cutaneous-only … association study
(GWAS) of 1,430 PsA case subjects and 1,417 unaffected control subjects. Meta-analysis of …

Genome‐wide association analysis and genetic architecture of egg weight and egg uniformity in layer chickens

A Wolc, J Arango, P Settar, JE Fulton… - … Genetics, 2012 - Wiley Online Library
genetic markers to analyze quantitative traits has provided opportunities to discover their
genetic architecture … samples was used to describe genetic architecture and to make statistical …

Integrating image-based phenomics and association analysis to dissect the genetic architecture of temporal salinity responses in rice

MT Campbell, AC Knecht, B Berger, CJ Brien… - Plant …, 2015 - academic.oup.com
… To assess the genetic basis of plant growth … association mapping. Coupled with temporal
fluorescence imaging, we present, to our knowledge, new insights into the genetic architecture

Determination of the genetic architecture of seed size and shape via linkage and association analysis in soybean (Glycine max L. Merr.)

Z Hu, H Zhang, G Kan, D Ma, D Zhang, G Shi, D Hong… - Genetica, 2013 - Springer
… In this study, we performed a genetic analysis to determine the genetic architecture of
soybean seed size and shape via linkage and association analyses. We used 184 recombinant …

[HTML][HTML] Genetic Architecture of Aluminum Tolerance in Rice (Oryza sativa) Determined through Genome-Wide Association Analysis and QTL Mapping

AN Famoso, K Zhao, RT Clark, CW Tung… - … genetics, 2011 - journals.plos.org
… a smaller target region following GWA analysis. In this study, the genetic architecture of rice
Al tolerance was investigated via bi-parental QTL analysis in two mapping populations using …

[HTML][HTML] The genetic architecture of appendicular lean mass characterized by association analysis in the UK Biobank study

YF Pei, YZ Liu, XL Yang, H Zhang, GJ Feng… - Communications …, 2020 - nature.com
… wide association study (GWAS) with 450,243 UK Biobank participants to uncover its genetic
architecture… Our findings revealed a large number of genetic variants for lean body mass and …