A genome-wide association scan identifies the hepatic cholesterol transporter ABCG8 as a susceptibility factor for human gallstone disease
… With an overall prevalence of 10–20%, gallstone disease (cholelithiasis) represents one of
… We performed an association scan of >500,000 SNPs in 280 individuals with gallstones and …
… We performed an association scan of >500,000 SNPs in 280 individuals with gallstones and …
Four susceptibility loci for gallstone disease identified in a meta-analysis of genome-wide association studies
… The UGT1A1 SNP rs6742078 did not show an overall association with gallstone disease in
log-additive models of our discovery data set (P < .114). However, in the NHS and the HPFS …
log-additive models of our discovery data set (P < .114). However, in the NHS and the HPFS …
Screen-detected gallstone disease and cardiovascular disease
… the liver, however the results of this study do not support these changes to have an independent
association with CVD but support that gallstone disease itself is associated with CVD. …
association with CVD but support that gallstone disease itself is associated with CVD. …
[HTML][HTML] Gallstone disease and the risk of cardiovascular disease
… reported a stronger association in mild gallstone disease (HR … of gallstone disease included
both history of gallstones and … be superior to gallstone disease diagnosis in discriminating …
both history of gallstones and … be superior to gallstone disease diagnosis in discriminating …
[PDF][PDF] Identification and replication of six loci associated with gallstone disease
H Gellert‐Kristensen, N Dalila… - …, 2019 - Wiley Online Library
… We aimed to identify genetic associations with gallstone disease … We extracted genetic
associations with gallstone disease from … A genome-wide association scan identifies the hepatic …
associations with gallstone disease from … A genome-wide association scan identifies the hepatic …
[HTML][HTML] Bidirectional association between nonalcoholic fatty liver disease and gallstone disease: a cohort study
… association between NAFLD and gallstones may be diluted due to the different pathogenesis
of gallstone … the bidirectional association between NAFLD and gallstones are incompletely …
of gallstone … the bidirectional association between NAFLD and gallstones are incompletely …
Prevalence and risk factors for gallstone disease
G Salinas, C Velásquez, L Saavedra… - Surgical Laparoscopy …, 2004 - journals.lww.com
… to 75 years were examined with the ultrasound scan. A 7-hour fasting period … gallstone
patients, we found a positive association between familial history of lithiasis and gallstone disease…
patients, we found a positive association between familial history of lithiasis and gallstone disease…
Gallstone disease and its association with nonalcoholic fatty liver disease, all-cause and cause-specific mortality
P Konyn, O Alshuwaykh, BB Dennis… - Clinical …, 2023 - Elsevier
… disease processes, further research is needed to better understand the relationship between
gallstone disease … In this study, we investigated the association between gallstone disease …
gallstone disease … In this study, we investigated the association between gallstone disease …
Obesity, adiposity, and risk of symptomatic gallstone disease according to genetic susceptibility
… have comprehensively characterized joint associations of genetic and environmental
factors … gallstone disease. Thus, our objective was to characterize the joint associations of a …
factors … gallstone disease. Thus, our objective was to characterize the joint associations of a …
[PDF][PDF] Gallstone disease and type 2 diabetes risk: a Mendelian randomization study
F Wang, J Wang, Y Li, J Yuan, P Yao, S Wei… - …, 2019 - Wiley Online Library
… A genome-wide association scan identifies the hepatic cholesterol transporter ABCG8 as a
susceptibility factor for human gallstone disease. Nat Genet 2007;39:995-999. 27) Rodriguez …
susceptibility factor for human gallstone disease. Nat Genet 2007;39:995-999. 27) Rodriguez …
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