… in the susceptibility to develop asthma and novel insights in the modulation of epithelial …
asthma. In this review, we will focus on airway epithelial barrier dysfunction as driver of asthma. …

… biopsies, whole mount immunofluorescence confocal microscopy with antibodies directed
to ZO-1 and occludin confirmed poorly developed TJs in asthmatic compared with normal …

… 228, suggesting that exogenous IFN-β may reduce the severity of asthma … of asthma
development. Clinical trials using inhaled IFN-β during respiratory viral infections in asthma have …

… cells of patients with asthma. Xiao et al.cultivated airway epithelial cells obtained from patients
with asthma … function of differentiated airway epithelial cells. These findings indicated that …

… in asthmatic airway epithelium. In this review, the roles of the EGFR family in asthmatic airway
… are focused on to elucidate the pathogenesis of airway epithelial dysfunction in asthma. …

… on asthma is also reinforced. In this review, I summarize the recent studies on metabolic
dysfunction and asthma, as well as the suggested mechanisms of asthma aggravation (Fig. 1). …

… Here, we review and discuss the current role and mechanism of epithelial barrier dysfunction
in developing allergic diseases and the effect of current allergy therapies on epithelial …

… of asthma in these individuals. Substantial evidence suggests that the persistence of asthma
is … dysfunction. The epithelium is both a site of production of these mediators and a source of …

… dysfunction is recognized in obesity-associated asthma, but … to be independently related to
asthma. Novel insights have … metabolic dysfunction in asthma, from obesity-related asthma to …

… dysfunction, leading to key features of allergic asthma. Dysregulations in autophagy, mitophagy,
and cellular … dysfunction, secretion of multiple inflammatory proteins, and subsequently …