Astrocytic Ca2+ signaling is reduced during sleep and is involved in the regulation of slow wave sleep
… astrocytic Ca 2+ signaling pathway impairs slow wave sleep … of slow wave sleep state
transitions and sleep spindles. Our … for astrocytic Ca 2+ signaling in regulating slow wave sleep. …
transitions and sleep spindles. Our … for astrocytic Ca 2+ signaling in regulating slow wave sleep. …
Region-specific and state-dependent astrocyte Ca2+ dynamics during the sleep-wake cycle in mice
T Tsunematsu, S Sakata, T Sanagi… - Journal of …, 2021 - Soc Neuroscience
… there are dynamic differences in astrocyte Ca 2+ levels among the … astrocyte Ca 2+ dynamics
of the cerebellum, cortex, hippocampus, hypothalamus, and pons of mice during the sleep-…
of the cerebellum, cortex, hippocampus, hypothalamus, and pons of mice during the sleep-…
Distinct astrocytic modulatory roles in sensory transmission during sleep, wakefulness, and arousal states in freely moving mice
… astrocytic Ca 2+ signals in the murine barrel cortex: a small, long-lasting Ca 2+ increase
during sleep and a large, widespread but short-lasting Ca 2+ spike when aroused. The large …
during sleep and a large, widespread but short-lasting Ca 2+ spike when aroused. The large …
[HTML][HTML] Astrocytic calcium waves: unveiling their roles in sleep and arousal modulation
… The identification of distinct patterns of astrocytic Ca 2+ signaling during different brain …
patterns of astrocytic Ca 2+ transients, astrocytes contribute to the overall balance of sleep, …
patterns of astrocytic Ca 2+ transients, astrocytes contribute to the overall balance of sleep, …
Goodnight, astrocyte: waking up to astroglial mechanisms in sleep
AM Ingiosi, MG Frank - The FEBS journal, 2023 - Wiley Online Library
… Ca 2+ activity in vivo and ex vivo revealed that astrocyte Ca 2+ levels change across the
sleep–wake cycle in ways that suggest they encode sleep … astrocytes and sleep, see [[19]]). …
sleep–wake cycle in ways that suggest they encode sleep … astrocytes and sleep, see [[19]]). …
Astrocytic IP3/Ca2+ Signaling Modulates Theta Rhythm and REM Sleep
J Foley, T Blutstein, SY Lee, C Erneux… - Frontiers in neural …, 2017 - frontiersin.org
… their intracellular Ca 2+ concentration. The goal of this study was to assess the sleep
architecture of mice with attenuated IP 3 mediated Ca 2+ signaling in astrocytes. Vigilance states …
architecture of mice with attenuated IP 3 mediated Ca 2+ signaling in astrocytes. Vigilance states …
[HTML][HTML] A role for astroglial calcium in mammalian sleep and sleep regulation
AM Ingiosi, CR Hayworth, DO Harvey, KG Singletary… - Current Biology, 2020 - cell.com
… intracellular calcium in astrocytes impairs the homeostatic response to sleep deprivation.
Thus… changes in Ca 2 + signals were uniform throughout the astrocyte or compartmentalized in …
Thus… changes in Ca 2 + signals were uniform throughout the astrocyte or compartmentalized in …
Ca2+ signaling in astrocytes is sleep-wake state specific and modulates sleep
… astrocytic Ca 2+ signals. We show that Ca 2+ signaling in astrocytes is reduced during sleep
compared to wakefulness and exhibits distinct characteristics across different sleep states. …
compared to wakefulness and exhibits distinct characteristics across different sleep states. …
Astrocytic modulation of sleep homeostasis and cognitive consequences of sleep loss
… Since the sleep-suppressing effects of the A1 receptor … that astrocytes modulate the
accumulation of sleep pressure and its … However, we find no perturbation in afferent-induced Ca …
accumulation of sleep pressure and its … However, we find no perturbation in afferent-induced Ca …
Noradrenergic signaling in astrocytes influences mammalian sleep homeostasis
AM Ingiosi, MG Frank - Clocks & Sleep, 2022 - mdpi.com
… that Ca 2+ activity of frontal cortex astrocytes—which we previously showed changes with
vigilance states and sleep … (5 mg/kg; intraperitoneally; Ca 2+ event frequency: U = 1350.00, p < …
vigilance states and sleep … (5 mg/kg; intraperitoneally; Ca 2+ event frequency: U = 1350.00, p < …