Astrocytic Ca2+ signaling is reduced during sleep and is involved in the regulation of slow wave sleep

L Bojarskaite, DM Bjørnstad, KH Pettersen… - Nature …, 2020 - nature.com
astrocytic Ca 2+ signaling pathway impairs slow wave sleep … of slow wave sleep state
transitions and sleep spindles. Our … for astrocytic Ca 2+ signaling in regulating slow wave sleep. …

Region-specific and state-dependent astrocyte Ca2+ dynamics during the sleep-wake cycle in mice

T Tsunematsu, S Sakata, T Sanagi… - Journal of …, 2021 - Soc Neuroscience
… there are dynamic differences in astrocyte Ca 2+ levels among the … astrocyte Ca 2+ dynamics
of the cerebellum, cortex, hippocampus, hypothalamus, and pons of mice during the sleep-…

Distinct astrocytic modulatory roles in sensory transmission during sleep, wakefulness, and arousal states in freely moving mice

F Wang, W Wang, S Gu, D Qi, NA Smith… - Nature …, 2023 - nature.com
astrocytic Ca 2+ signals in the murine barrel cortex: a small, long-lasting Ca 2+ increase
during sleep and a large, widespread but short-lasting Ca 2+ spike when aroused. The large …

[HTML][HTML] Astrocytic calcium waves: unveiling their roles in sleep and arousal modulation

E Wu, D Qi, D Nizamutdinov… - Neural Regeneration …, 2024 - journals.lww.com
… The identification of distinct patterns of astrocytic Ca 2+ signaling during different brain …
patterns of astrocytic Ca 2+ transients, astrocytes contribute to the overall balance of sleep, …

Goodnight, astrocyte: waking up to astroglial mechanisms in sleep

AM Ingiosi, MG Frank - The FEBS journal, 2023 - Wiley Online Library
Ca 2+ activity in vivo and ex vivo revealed that astrocyte Ca 2+ levels change across the
sleep–wake cycle in ways that suggest they encode sleepastrocytes and sleep, see [[19]]). …

Astrocytic IP3/Ca2+ Signaling Modulates Theta Rhythm and REM Sleep

J Foley, T Blutstein, SY Lee, C Erneux… - Frontiers in neural …, 2017 - frontiersin.org
… their intracellular Ca 2+ concentration. The goal of this study was to assess the sleep
architecture of mice with attenuated IP 3 mediated Ca 2+ signaling in astrocytes. Vigilance states …

[HTML][HTML] A role for astroglial calcium in mammalian sleep and sleep regulation

AM Ingiosi, CR Hayworth, DO Harvey, KG Singletary… - Current Biology, 2020 - cell.com
… intracellular calcium in astrocytes impairs the homeostatic response to sleep deprivation.
Thus… changes in Ca 2 + signals were uniform throughout the astrocyte or compartmentalized in …

Ca2+ signaling in astrocytes is sleep-wake state specific and modulates sleep

L Bojarskaite, DM Bjørnstad, KH Pettersen, C Cunen… - bioRxiv, 2019 - biorxiv.org
astrocytic Ca 2+ signals. We show that Ca 2+ signaling in astrocytes is reduced during sleep
compared to wakefulness and exhibits distinct characteristics across different sleep states. …

Astrocytic modulation of sleep homeostasis and cognitive consequences of sleep loss

MM Halassa, C Florian, T Fellin, JR Munoz, SY Lee… - Neuron, 2009 - cell.com
… Since the sleep-suppressing effects of the A1 receptor … that astrocytes modulate the
accumulation of sleep pressure and its … However, we find no perturbation in afferent-induced Ca

Noradrenergic signaling in astrocytes influences mammalian sleep homeostasis

AM Ingiosi, MG Frank - Clocks & Sleep, 2022 - mdpi.com
… that Ca 2+ activity of frontal cortex astrocytes—which we previously showed changes with
vigilance states and sleep … (5 mg/kg; intraperitoneally; Ca 2+ event frequency: U = 1350.00, p < …