[HTML][HTML] Mutation detection using plasma circulating tumor DNA (ctDNA) in a cohort of asymptomatic adults at increased risk for cancer

A Kammesheidt, TR Tonozzi, SW Lim… - International journal of …, 2018 - ncbi.nlm.nih.gov
… was to clinically evaluate circulating tumor DNA (ctDNA) with a … Subjects and Methods: DNA
from 1059 asymptomatic subjects … Analysis of buffy coat DNA from eight positive subjects, …

Circulating tumor DNA assays in clinical cancer research

MR Ossandon, L Agrawal, EJ Bernhard… - JNCI: Journal of the …, 2018 - academic.oup.com
… For the use of ctDNA assays in other settings, such as detection of residual disease following
treatment for primary cancers or detection of tumors in screening asymptomatic individuals, …

Screening for colorectal cancer in asymptomatic average-risk adults: a guidance statement from the American College of Physicians

A Qaseem, CJ Crandall, RA Mustafa… - Annals of internal …, 2019 - acpjournals.org
asymptomatic, average-risk adults, based on a critical review of existing guidelines and
their evidence reviews. This guidance statement does not address surveillance in patients with …

Circulating free tumor DNA and colorectal cancer

T Lecomte, N Ceze, E Dorval, P Laurent-Puig - … clinique et biologique, 2010 - Elsevier
… be useful as molecular markers for detecting tumor DNA in different bodily fluids. In patients
… of non-cell-bound DNA. In this free circulating DNA, tumor-associated molecular alterations …

Circulating-tumor DNA as an early detection and diagnostic tool

TM Butler, PT Spellman, J Gray - Current opinion in genetics & …, 2017 - Elsevier
The development of new circulating-tumor DNA (ctDNA) analysis techniques has led to an
explosion of studies demonstrating exciting clinical applications. Non-invasive genotyping …

Fecal DNA versus fecal occult blood for colorectal-cancer screening in an average-risk population

TF Imperiale, DF Ransohoff, SH Itzkowitz… - New England journal …, 2004 - Mass Medical Soc
… -based, multitarget DNA panel with Hemoccult II in asymptomatic adults, 50 years of … DNA
as the analyte is that a marker panel can be expanded or refined as knowledge about tumor

Impact of circulating tumor DNA–based detection of molecular residual disease on the conduct and design of clinical trials for solid tumors

PM Kasi, G Fehringer, H Taniguchi, N Starling… - JCO Precision …, 2022 - ascopubs.org
PURPOSE Earlier detection of cancer recurrence using circulating tumor DNA (ctDNA) to
detect molecular residual disease (MRD) has the potential to dramatically affect cancer …

Circulating tumor DNA (ctDNA) as a pan-cancer screening test: is it finally on the horizon?

MJ Duffy, EP Diamandis, J Crown - Clinical Chemistry and …, 2021 - degruyter.com
… Like proteins, tumor DNA also can be released into the circulation. Such circulating tumor
DNA (ctDNA) can be differentiated from … Sensitivity is likely to be less in asymptomatic subjects …

Association of circulating tumor DNA with disease-free survival in breast cancer: a systematic review and meta-analysis

C Cullinane, C Fleming, DP O'Leary… - JAMA network …, 2020 - jamanetwork.com
… The following search terms were used: ctDNA OR circulating tumor DNA OR liquid biopsy
AND breast cancer OR breast carcinoma OR breast tumor AND prognosis OR survival. All …

Colorectal and extracolonic cancers detected at screening CT colonography in 10 286 asymptomatic adults

PJ Pickhardt, DH Kim, RJ Meiners, KS Wyatt… - Radiology, 2010 - pubs.rsna.org
… of asymptomatic disease for these tumors, which often progress rapidly and typically manifest
as advanced. In addition, the low-dose, nonenhanced technique utilized for screening CT …