[HTML][HTML] Atezolizumab plus bevacizumab in unresectable hepatocellular carcinoma

RS Finn, S Qin, M Ikeda, PR Galle… - … England Journal of …, 2020 - Mass Medical Soc
… unresectable hepatocellular carcinoma who had not previously received systemic treatment
were randomly assigned in a 2:1 ratio to receive either atezolizumab plus bevacizumab or …

Atezolizumab and bevacizumab for hepatocellular carcinoma: Mechanism, pharmacokinetics and future treatment strategies

X Liu, Y Lu, S Qin - Future oncology, 2021 - Future Medicine
cancer has already spread and are less likely to survive. A new treatment method using two
kinds of antibodies, atezolizumab and bevacizumab… with advanced liver cancer. In this review…

[HTML][HTML] Updated efficacy and safety data from IMbrave150: Atezolizumab plus bevacizumab vs. sorafenib for unresectable hepatocellular carcinoma

AL Cheng, S Qin, M Ikeda, PR Galle, M Ducreux… - Journal of …, 2022 - Elsevier
… IMbrave150 demonstrated that atezolizumab plus bevacizumab led to significantly … with
sorafenib in patients with unresectable hepatocellular carcinoma at the primary analysis (after a …

Atezolizumab with or without bevacizumab in unresectable hepatocellular carcinoma (GO30140): an open-label, multicentre, phase 1b study

MS Lee, BY Ryoo, CH Hsu, K Numata, S Stein… - The Lancet …, 2020 - thelancet.com
… suggest that combining atezolizumab with bevacizumab can … patients with unresectable
hepatocellular carcinoma. To find … done to compare atezolizumab and bevacizumab combination …

FDA approval summary: atezolizumab plus bevacizumab for the treatment of patients with advanced unresectable or metastatic hepatocellular carcinoma

SJ Casak, M Donoghue, L Fashoyin-Aje, X Jiang… - Clinical Cancer …, 2021 - AACR
atezolizumab for use in combination with bevacizumab, for … advanced or metastatic
hepatocellular carcinoma (HCC) with … atezolizumab plus bevacizumab (atezolizumab-bevacizumab) …

Molecular correlates of clinical response and resistance to atezolizumab in combination with bevacizumab in advanced hepatocellular carcinoma

AX Zhu, AR Abbas, MR de Galarreta, Y Guan, S Lu… - Nature medicine, 2022 - nature.com
… Molecular correlates of clinical response to atezolizumab-bevacizumab To explore potential
biomarkers associated with clinical response or resistance to atezolizumab + bevacizumab, …

Effectiveness and safety of atezolizumab-bevacizumab in patients with unresectable hepatocellular carcinoma: a systematic review and meta-analysis

AV Kulkarni, H Tevethia, K Kumar, M Premkumar… - …, 2023 - thelancet.com
Atezolizumab-bevacizumab (atezo-bev) is recommended as first-line therapy for patients
with unresectable hepatocellular carcinoma (uHCC). However, its effectiveness and safety in …

[HTML][HTML] … evaluating atezolizumab (atezo)+ bevacizumab (bev) vs sorafenib (Sor) as first treatment (tx) for patients (pts) with unresectable hepatocellular carcinoma  …

AL Cheng, S Qin, M Ikeda, P Galle, M Ducreux, A Zhu… - Annals of …, 2019 - Elsevier
Background Ph 1b data has shown promising efficacy and safety for atezo + bev in unresectable
HCC pts who have not received prior systemic therapy. Here, we report the primary …

First-line targeted therapy for hepatocellular carcinoma: role of atezolizumab/bevacizumab combination

SH Tella, A Kommalapati, A Mahipal, Z Jin - Biomedicines, 2022 - mdpi.com
… the combination of atezolizumabbevacizumab, sorafenib, … approved the use of
atezolizumabbevacizumab, sorafenib, … including atezolizumab plus a bevacizumab combination …

Atezolizumab-bevacizumab plus Y-90 TARE for the treatment of hepatocellular carcinoma: preclinical rationale and ongoing clinical trials

A Di Federico, A Rizzo, R Carloni… - Expert Opinion on …, 2022 - Taylor & Francis
… combination with other agents (eg bevacizumab, lenvatinib), have … The combination of
atezolizumab and bevacizumab has … with atezolizumab, VEGF blockade with bevacizumab and a …