… Antibodies against an … the development of atherosclerosis as well as to induce regression
of existing lesions in mice [78], [79]. The ability of these antibodies to reduce atherosclerosis …

… In contrast, we showed that autoantibodies against a solid phase β2-GPI complexed with
oxLig-1 were detected in sera of APS patients having episodes of arterial thrombosis and that …

… in development of atherosclerosis associated with decreased levels of Hsp antibodies and
… The possibility of inhibiting atherosclerosis by suppressing autoimmune responses against …

… atherosclerosis and subsequently to the generation of transgenic murine strains that develop
atherosclerotic … a monoclonal antibody against oxidativery modified LDL in atherosclerotic …

… within and without the autoimmune settting. Measurement of … of detecting subclinical
atherosclerosis. This technique has … antiphospholipid antibodies and premature atherosclerosis. …

… of atherosclerosis and provide examples of how emerging technologies may be used to
accelerate the pace of discovery and facilitate development of novel therapeutic approaches. …

… autoimmune-mediated atherosclerosis is developed in the APS patients (Figure 3). Further,
animal models of human APS attractively demonstrated proatherogenicity of anti-β2-GPI Abs…

… [3] [4] In fact, cardiovascular disease (CVD), one of the main causes of mortality in SLE, is
known to be related to early atherosclerosis development.[5] Of note, the incidence of …

… association between markers of subclinical atherosclerosis and the presence of antibodies
against ox-LDL has been depicted in our SLE patients in accord with previous observations (…

… autoimmunity in atherosclerosis. Some germinal centre B cells become plasma cells and
secrete antibodies to atherosclerosis-associated antigens including oxidized LDL (not shown). …