Histone deacetylases and atherosclerosis

X Zheng, T Zhou, XA Wang, X Tong, J Ding - Atherosclerosis, 2015 - Elsevier
atherosclerosis and the stability of plaque. In addition, HDAC2 also function as a regulator of
non-histone proteins and modulates the deacetylation … the development of atherosclerosis. …

Histone deacetylases (HDACs) and atherosclerosis: A mechanistic and pharmacological review

X Chen, Y He, W Fu, A Sahebkar, Y Tan… - Frontiers in Cell and …, 2020 - frontiersin.org
… Accumulating evidence has suggested the critical roles of histone deacetylases (HDACs) in
regulating … We also elaborate on the novel therapeutic targets and agents in atherosclerotic

Role of histone deacetylase Sirt3 in the development and regression of atherosclerosis

Y Liu, X Shen, M Pang, Z Sun, Y Qian, W Xue, Z Wang… - Life Sciences, 2021 - Elsevier
… This review combining histone deacetylase Sirt3 with AS, aims to clarify the latest progress
in the significant role of Sirt3 in the development and regression of AS and to provide a novel …

New role for histone deacetylase 9 in atherosclerosis and inflammation

JD Smith - Arteriosclerosis, thrombosis, and vascular biology, 2014 - Am Heart Assoc
Histone acetylation is reversible, allowing for environmental and developmental gene … this
process is performed by members of the histone deacetylase (HDAC) gene family. There are 5 …

[HTML][HTML] Histone deacetylase 3: a potential therapeutic target for atherosclerosis

LP Jiang, XH Yu, JZ Chen, M Hu, YK Zhang… - Aging and …, 2022 - ncbi.nlm.nih.gov
… and lipid accumulation that cause atherosclerosis. Histone deacetylase (HDAC) is an …
family has cell-specific functions in atherosclerosis, including 1) maintenance of endothelial …

The important role of histone deacetylases in modulating vascular physiology and arteriosclerosis

TC Zhao, Z Wang, TY Zhao - Atherosclerosis, 2020 - Elsevier
… of histone deacetylase in modulating the development of vascular cells as well as atherosclerosis,
… partners in controlling vascular cell development and modulating the progression of …

Histone deacetylase 3 is critical in endothelial survival and atherosclerosis development in response to disturbed flow

A Zampetaki, L Zeng, A Margariti, Q Xiao, H Li… - Circulation, 2010 - Am Heart Assoc
Histone deacetylases (HDACs) have previously been shown to be important in the biology
of endothelial progenitor cells, 8 but their role in atherosclerosis prone areas is unknown. …

Histone deacetylase 9 represses cholesterol efflux and alternatively activated macrophages in atherosclerosis development

Q Cao, S Rong, JJ Repa, RS Clair… - … , and vascular biology, 2014 - Am Heart Assoc
… in the loci corresponding to histone deacetylase 9 (HDAC9) is … atherosclerotic plaques
in different arteries. The molecular mechanisms how HDAC9 might increase atherosclerosis

Role of histone deacetylases in vascular cell homeostasis and arteriosclerosis

B Zhou, A Margariti, L Zeng, Q Xu - Cardiovascular research, 2011 - academic.oup.com
Histone deacetylation has been shown to have a link to atherosclerosis. HDACs are enzymes
that … Except their roles in gene repression via histone deacetylation, HDACs can also …

Targeting macrophage Histone deacetylase 3 stabilizes atherosclerotic lesions

MA Hoeksema, MJJ Gijbels… - EMBO molecular …, 2014 - embopress.org
… may hold novel approaches for future atherosclerosis management. Here, we describe a …
epigenomic enzyme Histone deacetylase 3 (Hdac3) in regulating the atherosclerotic phenotype …