Circulating oxidized LDL is associated with subclinical atherosclerosis development and inflammatory cytokines (AIR Study)

J Hulthe, B Fagerberg - Arteriosclerosis, thrombosis, and vascular …, 2002 - Am Heart Assoc
… among oxidized LDL (Ox-LDL), atherosclerotic changes in … Ox-LDL was associated with
both subclinical atherosclerosis … Ox-LDL may be of importance in atherosclerosis development. …

Antibodies to oxidized LDL in atherosclerosis development—clinical and animal studies

J Hulthe - Clinica chimica acta, 2004 - Elsevier
… Therefore, the aim of this paper is to make an overview of clinical studies investigating the
relationship between atherosclerosis and antibody titers to oxidized LDL, and also to relate …

Mechanisms of oxidized LDL-mediated endothelial dysfunction and its consequences for the development of atherosclerosis

H Jiang, Y Zhou, SM Nabavi, A Sahebkar… - Frontiers in …, 2022 - frontiersin.org
… A series of pathophysiological changes caused by oxidized LDL (oxLDL) enhance the
formation of foam cells and atherosclerotic plaques. OxLDL also promotes the development of …

Role of oxidized LDL and antioxidants in atherosclerosis

D Steinberg - Nutrition and biotechnology in heart disease and …, 1995 - Springer
… " was a necessary first step in the development of atherosclerotic lesions. That concept was
… of atherosclerosis but it only becomes a dominant process later in lesion development. We …

Oxidative stress in atherosclerosis development: the central role of LDL and oxidative burst

I Peluso, G Morabito, L Urban… - … , metabolic & immune …, 2012 - ingentaconnect.com
… Macrophages exposed to oxidized LDL (oxLDL) express … in the development of
atherosclerotic plaques and CVD … the free radicals induced LDL modifications by leukocytes and …

The dynamics of oxidized LDL during atherogenesis

H Itabe, T Obama, R Kato - Journal of lipids, 2011 - Wiley Online Library
… ApoE-KO mice develop atherosclerotic lesions even when fed normal diet. The lesion area
was less than 1% of the whole aortic surface at 10 weeks, but it gradually increased after 20 …

Oxidized LDL and HDL: antagonists in atherothrombosis

ANN Mertens, P Holvoet - The FASEB journal, 2001 - Wiley Online Library
Oxidized LDL induces atherosclerosis by stimulating … levels of circulating oxidized LDL
predict the development of … that oxidized LDL plays an active role in the development of CAD. …

Oxidized LDL, a critical factor in atherogenesis

D Li, JL Mehta - Cardiovascular research, 2005 - academic.oup.com
… -LDL in atherosclerosis was first established through the use of the antioxidant probucol in
atherosclerosis-… state is present in all stages of atherosclerosis from the beginning to the acute …

Oxidized LDL, LOX-1 and atherosclerosis

S Mitra, T Goyal, JL Mehta - Cardiovascular drugs and therapy, 2011 - Springer
… in the development and progression of atherosclerosis and … atherosclerosis. Fatty streaks
are small sub-endothelial deposits of monocyte-derived macrophages. Oxidized LDL (ox-LDL) …

The role of oxidized LDL in atherosclerosis

JL Witztum - … , Hypocholesterolemia, Hypertriglyceridemia, in Vivo …, 1990 - Springer
… to demonstrate that oxidized LDL occurs in vivo. Our group in La Jolla have recently
developed a number of lines of evidence that in fact suggest that oxidized LDL does exist in the …