Natural antibodies against phosphorylcholine in cardiovascular disease
U De Faire, J Frostegård - Annals of the New York Academy of …, 2009 - Wiley Online Library
… atherosclerosis development in hypertensive individuals and that low levels of anti-PC
independently predict development … -PC ameliorate atherosclerosis development. The possibility …
independently predict development … -PC ameliorate atherosclerosis development. The possibility …
[HTML][HTML] IgM phosphorylcholine antibodies inhibit cell death and constitute a strong protection marker for atherosclerosis development, particularly in combination with …
R Fiskesund, J Su, I Bulatovic, M Vikström… - Results in …, 2012 - Elsevier
… p-nitrophenyl phosphorylcholine (NPPC) whereas Group II antibodies require the phenyl …
anti-PC antibodies with focus on anti-inflammation in atherosclerosis. After developing a …
anti-PC antibodies with focus on anti-inflammation in atherosclerosis. After developing a …
Low level natural antibodies against phosphorylcholine: a novel risk marker and potential mechanism in atherosclerosis and cardiovascular disease
J Frostegård - Clinical immunology, 2010 - Elsevier
… Already in the 1970s, Russell Ross hypothesized that a ‘response to injury’ was essential
in atherosclerosis development and the discussed potential underlying factors are compatible …
in atherosclerosis development and the discussed potential underlying factors are compatible …
Antibodies against phosphorylcholine and protection against atherosclerosis, cardiovascular disease and chronic inflammation
J Frostegård - Expert Review of Clinical Immunology, 2022 - Taylor & Francis
… atherosclerosis, which is the main topic herein, not only because CVD and atherosclerosis …
because much more is known about phosphorylcholine (PC) and antibodies against PC (anti-…
because much more is known about phosphorylcholine (PC) and antibodies against PC (anti-…
Phosphorylcholine-targeting immunization reduces atherosclerosis
G Caligiuri, J Khallou-Laschet, M Vandaele… - Journal of the American …, 2007 - jacc.org
… Active PC immunization resulted in activation of the B-cell compartment in parallel with
enrichment of B cells and T15-like antibodies within the atherosclerotic plaques where their …
enrichment of B cells and T15-like antibodies within the atherosclerotic plaques where their …
Antibodies against native and oxidized cardiolipin and phosphatidylserine and phosphorylcholine in atherosclerosis development
AG Frostegård, J Su, X Hua, M Vikström, U de Faire… - PLoS …, 2014 - journals.plos.org
… IgM antibodies against phosphorylcholine (anti-PC) are protection factors for atherosclerosis
… house ELISA [3], and it is possible that low levels of such antibodies predispose to CVD [2]. …
… house ELISA [3], and it is possible that low levels of such antibodies predispose to CVD [2]. …
Identification of IgG1 isotype phosphorylcholine antibodies for the treatment of inflammatory cardiovascular diseases
MR de Vries, MM Ewing, RCM de Jong… - Journal of Internal …, 2021 - Wiley Online Library
… to develop a monoclonal PC IgG antibody with anti-inflammatory and anti-atherosclerotic …
The current project aimed to develop a fully human monoclonal PC antibody (PC-mAb) for the …
The current project aimed to develop a fully human monoclonal PC antibody (PC-mAb) for the …
Antibodies against Phosphorylcholine—Implications for Chronic Inflammatory Diseases
J Frostegård - Metabolites, 2023 - mdpi.com
… It is thus important to emphasize that PC is not exposed to any significant degree in the
normal artery, which occurs much more in arteries where atherosclerosis is developing. …
normal artery, which occurs much more in arteries where atherosclerosis is developing. …
Low levels of IgM antibodies against phosphorylcholine predict development of acute myocardial infarction in a population-based cohort from northern Sweden
H Grönlund, G Hallmans, JH Jansson… - European Journal of …, 2009 - academic.oup.com
… of CVD and atherosclerosis. We recently reported a negative association between levels
of antibodies against phosphorylcholine (anti-PC) IgM and development of atherosclerosis in …
of antibodies against phosphorylcholine (anti-PC) IgM and development of atherosclerosis in …
Low levels of IgM antibodies against phosphorylcholine—a potential risk marker for ischemic stroke in men
BG Sjöberg, J Su, I Dahlbom, H Grönlund, M Wikström… - Atherosclerosis, 2009 - Elsevier
… Natural antibodies specific for phosphorylcholine (anti-PC) have been implicated as
protective factors in atherosclerosis. We herein determined the relationship between IgM anti-PC …
protective factors in atherosclerosis. We herein determined the relationship between IgM anti-PC …
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