Early immunologic changes during the onset of atopic dermatitis
PM Brunner - Annals of Allergy, Asthma & Immunology, 2019 - Elsevier
… Atopic dermatitis (AD), which is commonly called eczema, is … is currently expanding, a
development that is largely based on our … In addition to aberrant immune activation, a defect in …
development that is largely based on our … In addition to aberrant immune activation, a defect in …
Atopic dermatitis-like disease and associated lethal myeloproliferative disorder arise from loss of Notch signaling in the murine skin
A Dumortier, AD Durham, M Di Piazza, S Vauclair… - PloS one, 2010 - journals.plos.org
… RBP-J, induces the development of a severe form of atopic dermatitis (AD), characterized by
… the phenotype observed was not due to aberrant Cre-recombinase activity in hematopoietic …
… the phenotype observed was not due to aberrant Cre-recombinase activity in hematopoietic …
Atopic dermatitis: immune deviation, barrier dysfunction, IgE autoreactivity and new therapies
M Furue, T Chiba, G Tsuji, D Ulzii… - Allergology …, 2017 - jstage.jst.go.jp
… Th2 and T22 differentiation, elevated IgE is likely to be engaged in the development …
aureus colonization contribute to disease progression and aberrant IgE production in AD.64e66 …
aureus colonization contribute to disease progression and aberrant IgE production in AD.64e66 …
In vitro genetically aberrant T-cell clones with continuous growth are associated with atopic dermatitis
K Kaltoft, CB Pedersen, BH Hansen… - Archives of …, 1994 - Springer
… autonomous paracrine growth of atopic T-cell lines followed by the development of clonal
chro… The results of this investigation suggest that a subset of aberrant skin-homing T cells is as…
chro… The results of this investigation suggest that a subset of aberrant skin-homing T cells is as…
The etiopathogenesis of atopic dermatitis: barrier disruption, immunological derangement, and pruritus
P Rerknimitr, A Otsuka, C Nakashima… - Inflammation and …, 2017 - Springer
… aberrant profilaggrin polypeptide expression while ma mutation gives rise to the matted hair
and spontaneous dermatitis … (FLG) in the development of atopic dermatitis. Decreased FLG …
and spontaneous dermatitis … (FLG) in the development of atopic dermatitis. Decreased FLG …
The incidence and pathophysiology of atopic dermatitis
K Thestrup-Pedersen - Journal of the European Academy of Dermatology …, 1996 - Elsevier
… We hypothesize that the maturation of the T cell immune system is disturbed, resulting in a …
genetically aberrant T cell clones with continuous growth is associated with atopic dermatitis. …
genetically aberrant T cell clones with continuous growth is associated with atopic dermatitis. …
Subtypes of atopic dermatitis: From phenotype to endotype
Y Tokura, S Hayano - Allergology International, 2022 - jstage.jst.go.jp
Atopic dermatitis (AD) is a heterogenous disorder and can be classified into different types.
Stratification of subtypes may enable personalized medicine approaches. AD can be …
Stratification of subtypes may enable personalized medicine approaches. AD can be …
Molecular mechanisms of atopic dermatitis pathogenesis
J Sroka-Tomaszewska, M Trzeciak - International journal of molecular …, 2021 - mdpi.com
… is one of the determinants of AD development, next to the FLG gene polymorphisms and …
exposure to the development of AD or allergy to food allergens in the first years of life [36]. …
exposure to the development of AD or allergy to food allergens in the first years of life [36]. …
Alterations in B-cell subsets in pediatric patients with early atopic dermatitis
T Czarnowicki, H Esaki, J Gonzalez… - Journal of Allergy and …, 2017 - Elsevier
… Results show that early-onset AD is characterized by aberrant B-cell maturation, T-cell
predominance, and a complex network of associations between activated memory T cells, B cells, …
predominance, and a complex network of associations between activated memory T cells, B cells, …
The maturation‐dependent production of interleukin‐16 is impaired in monocyte‐derived dendritic cells from atopic dermatitis patients but is restored by inflammatory …
K Reich, S Hugo, P Middel, V Blaschke… - Experimental …, 2004 - Wiley Online Library
… in monocytes from atopic donors account for the aberrant maturation and cytokine … atopy
patch test reactions (23) and promote DC maturation (18). Parallel to the phenotypic maturation …
patch test reactions (23) and promote DC maturation (18). Parallel to the phenotypic maturation …
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