Sweat in the pathogenesis of atopic dermatitis

H Murota, K Yamaga, E Ono, I Katayama - Allergology International, 2018 - jstage.jst.go.jp
… of sweat glands in atopic dermatitis. “In atopic dermatitis lesional skin, obstruction of sweat
gland by a keratotic plug or by mucopolysaccharides, leakage of sweat from the sweat glands

Why does sweat lead to the development of itch in atopic dermatitis?

H Murota, K Yamaga, E Ono… - Experimental …, 2019 - Wiley Online Library
… Current understanding of the mechanism of sweat-related itch in atopic dermatitis. Sweat
gland damage and change in sweat components induced by inflammation make skin prone to …

Sweat mechanisms and dysfunctions in atopic dermatitis

AJ Hendricks, AR Vaughn, AK Clark… - Journal of …, 2018 - Elsevier
… solution secreted by eccrine sweat glands. In addition to … Cholinergic stimulation of sweat
gland cells via muscarinic ACh … , which prevents cholinergic stimulation of sweat glands [12]. …

A novel method to assess the potential role of sweating abnormalities in the pathogenesis of atopic dermatitis

Y Shimoda‐Komatsu, Y Sato… - Experimental …, 2018 - Wiley Online Library
… We found that sweating defects in AD initially occurs in some sweat glands/ducts at the
dermal folds which could be associated with compensatory hyperhidrosis in those at the dermal …

Claudin-3 loss causes leakage of sweat from the sweat gland to contribute to the pathogenesis of atopic dermatitis

K Yamaga, H Murota, A Tamura, H Miyata… - Journal of Investigative …, 2018 - Elsevier
… claudins are expressed in murine sweat glands, we found that … Atopic dermatitis lesional
skin had decreased claudin-3 expression in sweat glands, which was accompanied by sweat

Quantity and quality of sweating in atopic dermatitis

M Wruhs, A Gleiß, A Steiner, P Sator - Archives of Dermatological …, 2017 - Springer
… Our findings suggest that a deficient innervation of sweat glands in atopic patients … atopic
dermatitis sweat more, their eczema worsens in summertime and the qualitative sweat gland is …

Defective sweating responses in atopic dermatitis

T Shiohara, T Doi, J Hayakawa - … and Management of Atopic Dermatitis, 2011 - karger.com
sweating response with delayed kinetics can be paradoxically detected in some sweating
glands … exclusively produced by sweat glands, was abundantly detected not only in the sweat

[HTML][HTML] Exacerbating factors of itch in atopic dermatitis

H Murota, I Katayama - Allergology International, 2017 - Elsevier
… In addition, we have recently discovered that histamine suppresses perspiration by
affecting the sweat gland. In other words, allergic inflammation can be a cause of decreased …

Histamine modulates sweating and affects clinical manifestations of atopic dermatitis

A Takahashi, S Tani, H Murota, I Katayama - Perspiration Research, 2016 - karger.com
… Another mechanism is an abnormal production and secretion of sweat by sweat glands,
reportedly via an autonomic imbalance or decrease in the response to ACh [17]. In past reports, …

[引用][C] Atopic Dermatitis: II. Role of the Sweating Mechanism

L Tuft, HS Tuft, VM Heck - Journal of Investigative Dermatology, 1950 - Elsevier
… the glands are involved, sweating still may be brought about by the unaffected glands under
… the active allergenic excitant brought to the sweat glands through the circulating blood after …