Thymic stromal lymphopoietin, skin barrier dysfunction, and the atopic march

SF Ziegler - Annals of Allergy, Asthma & Immunology, 2021 - Elsevier
… that affect the development of atopic diseases and the atopic march, with a focus … stromal
lymphopoietin (TSLP), the target for the prevention of the atopic march and treatment of atopic

Current evidence of epidermal barrier dysfunction and thymic stromal lymphopoietin in the atopic march

M Li - European Respiratory Review, 2014 - Eur Respiratory Soc
… , leading to the subsequent development of other atopic diseases. This brief review will …
-derived cytokine thymic stromal lymphopoietin play critical roles in the onset of the atopic march. …

Thymic stromal lymphopoietin expression is increased in the horny layer of patients with atopic dermatitis

Y Sano, K Masuda… - Clinical & …, 2013 - academic.oup.com
… Thymic stromal lymphopoietin (TSLP) is known for its capacity to induce CD11c + myeloid
dendritic cells to promote T helper type 2 (Th2)-skewed inflammatory responses. Although …

Serum thymic stromal lymphopoietin in pediatric atopic patients and its relation to the development of the atopic march

R Genedy, C Farid, E Saad - Journal of the Egyptian Women's …, 2016 - journals.lww.com
… Thymic stromal lymphopoietin (TSLP) is an epithelial-derived cytokine with a … and
progression of atopic dermatitis (AD) through the atopic march has been experimentally …

Thymic stromal lymphopoietin and atopic diseases

JM Leyva-Castillo, M Li - Revue Française d'Allergologie, 2014 - Elsevier
atopic march. Studies using mouse models have provided strong evidences that TSLP plays
a critical role in the atopic march… role of skin TSLP in the atopic march, by employing a more …

Serum thymic stromal lymphopoietin (TSLP) levels in atopic dermatitis patients: a systematic review and meta-analysis

MM Garcia-Reyes, LC Zumaya-Perez… - Clinical and …, 2023 - Springer
… Thymic stromal lymphopoietin (TSLP) is critical in developing allergic responses, including
atopic dermatitis (AD). We systematically reviewed the literature to complete a meta-analysis …

Atopic dermatitis and the atopic march revisited

SC Dharmage, AJ Lowe, MC Matheson, JA Burgess… - Allergy, 2014 - Wiley Online Library
allergic phenotypes. The hypotheses on plausible biological mechanisms for the atopic march
… the skin affected by AD (including thymic stromal lymphopoietin). Both human and animal …

Increased serum thymic stromal lymphopoietin in children with atopic dermatitis

EB Lee, KW Kim, JY Hong, HM Jee… - Pediatric allergy and …, 2010 - Wiley Online Library
… The present study investigated the relationship between serum thymic stromal lymphopoietin
(TSLP) levels and the presence and severity of atopic dermatitis (AD). Serum TSLP levels, …

Might biologics serve to interrupt the atopic march?

JM Spergel, G Du Toit, CM Davis - Journal of Allergy and Clinical …, 2023 - Elsevier
… IL-13 preceded by induction of the alarmins (thymic stromal lymphopoietin, IL-33, and IL-25), …
that interact with T2 pathway represent possible ways to prevent or modify the atopic march. …

Thymic stromal lymphopoietin overproduced by keratinocytes in mouse skin aggravates experimental asthma

Z Zhang, P Hener, N Frossard, S Kato… - Proceedings of the …, 2009 - National Acad Sciences
… the “atopic march” remain elusive. In the present study, we show that induced expression of
thymic stromal lymphopoietin (… but also aggravates experimental allergic asthma induced by …