Cellular and molecular mechanisms of atrial arrhythmogenesis in patients with paroxysmal atrial fibrillation

N Voigt, J Heijman, Q Wang, DY Chiang, N Li… - Circulation, 2014 - Am Heart Assoc
… The latter type is likely associated with a reentrant mechanism. Whether, as one might
expect, the arrhythmogenic mechanisms identified in the present study are associated with …

[HTML][HTML] Obesity and atrial fibrillation: a narrative review from arrhythmogenic mechanisms to clinical significance

H Shu, J Cheng, N Li, Z Zhang, J Nie, Y Peng… - Cardiovascular …, 2023 - Springer
The prevalence of obesity and atrial fibrillation (AF), which are inextricably linked, is rapidly
increasing worldwide. Obesity rates are higher among patients with AF than healthy …

Novel mechanisms in the pathogenesis of atrial fibrillation: practical applications

DH Lau, U Schotten, R Mahajan, NA Antic… - European heart …, 2016 - academic.oup.com
… Current rhythm control strategies with anti-arrhythmic drugs are limited by the lack of atrial-specific
agents, modest efficacy, and significant toxicities including risk of pro-…

Mechanisms of atrial fibrillation

RS Wijesurendra, B Casadei - Heart, 2019 - heart.bmj.com
Arrhythmic mechanisms that sustain AF … More recent efforts have focused on identifying
the underlying cellular and molecular mechanisms that lead to atrial remodelling. Alterations in …

[PDF][PDF] New insights into mechanisms of atrial fibrillation.

B Aldhoon, V Melenovský, P Peichl, J Kautzner - Physiological research, 2010 - Citeseer
mechanisms responsible for the onset and persistence of the arrhythmia with emphasis on
the role of atrial … Together, these alterations create an arrhythmogenic substrate essential for …

Gut microbiota, dysbiosis and atrial fibrillation. Arrhythmogenic mechanisms and potential clinical implications

M Gawałko, TA Agbaedeng, A Saljic… - Cardiovascular …, 2022 - academic.oup.com
… in gut microbiota composition as a contributor to atrial fibrillation (AF). The gut microbiota
is a … We also discuss the potential anti-arrhythmic effects of pharmacological and diet-induced …

Fundamentals of arrhythmogenic mechanisms and treatment strategies for equine atrial fibrillation

A Premont, S Balthes, CM Marr… - Equine veterinary …, 2022 - Wiley Online Library
… knowledge of arrhythmogenic mechanisms at the cellular and tissue levels is extremely
sparse. Better understanding and characterisation of the underlying arrhythmogenic substrate …

[HTML][HTML] Atrial fibrillation and its arrhythmogenesis associated with insulin resistance

YH Chan, GJ Chang, YJ Lai, WJ Chen… - Cardiovascular …, 2019 - Springer
… To evaluate the arrhythmogenic mechanisms of HFa and HFr atria, we performed an optical
mapping study. The mapping area was focused on the right atrial appendage (RAA). Figure …

The value of basic research insights into atrial fibrillation mechanisms as a guide to therapeutic innovation: a critical analysis

J Heijman, V Algalarrondo, N Voigt… - Cardiovascular …, 2016 - academic.oup.com
… , 3,6 which disturb normal atrial electrophysiology, promoting focal ectopic activity and re-entry,
the fundamental arrhythmogenic mechanisms underlying AF initiation and maintenance (…

[HTML][HTML] Atrial fibrillation: pathogenesis, predisposing factors, and genetics

M Sagris, EP Vardas, P Theofilis… - International journal of …, 2021 - mdpi.com
arrhythmogenic substrate, with re-entry circuits enabling the perpetuation of atrial fibrillation
[… been associated with the development of atrial fibrillation through various mechanisms [49]. …