… of atrial fibrillation (AF) has been less clear. This review seeks to define the optimal dose and
… those who achieve a weekly physical activity dose slightly above the current recommended …

… Although the optimal dose, dosing interval, and duration of therapy is unclear, a single
dose given at induction may be adequate. The interaction between corticosteroids, β-blockers, …

… Atrial fibrillation (AF) is the most common sustained arrhythmia worldwide and the prev…
The analysis of the Atrial Fibrillation Investigators database observed a 45% increase of risk …

… We aim to determine the optimal dose of dabigatran in Korean patients with atrial fibrillation
(… Furthermore, to confirm whether dabigatran 110 mg is the optimal dose for Korean patients …

… To estimate optimal doses of the 3 FXa inhibitors, we carried out simulations of treatment
effects for various doses of each agent in virtual patient populations synthesized based on the …

… In conclusion, our findings raise questions about optimal dosing of apixaban in older adults
with NVAF outside of clinical trials. Drug concentrations were higher than expected based on …

… To inform decision-makers whether the common practice of dosing outside of guidelines
produces optimal patient outcomes, it is necessary to systematically evaluate the clinical and …

… doses of anticoagulant. The appropriate choice of treatment for these subgroups will help to
promote optimal … NOAC and/or dose in subgroups of patients with atrial fibrillation (AF) and …

… once daily (od) for stroke prevention in atrial fibrillation (AF). Based on rivaroxaban … optimal
dose regimen for Japanese AF patients was considered. The aim of this analysis was dose …

… Additional, PK/PD studies may be warranted to determine optimal dosing of NOACs among
specific patient cohorts such as those with chronic kidney disease, patients at low and high …