Combined metabolomic and proteomic analysis of human atrial fibrillation

M Mayr, S Yusuf, G Weir, YL Chung, U Mayr… - Journal of the American …, 2008 - jacc.org
Objectives : We sought to decipher metabolic processes servicing the increased energy
demand during persistent atrial fibrillation (AF) and to ascertain whether metabolic …

[HTML][HTML] Proteomic analysis of atrial appendages revealed the pathophysiological changes of atrial fibrillation

B Liu, X Li, C Zhao, Y Wang, M Lv, X Shi, C Han… - Frontiers in …, 2020 - frontiersin.org
… and some may further develop to atrial electrical remodeling by structural … proteomics
analysis identified 17 AF-associated proteins, which were mostly correlated to structural atrial

[HTML][HTML] Quantitative proteomic analysis to identify differentially expressed proteins in the persistent atrial fibrillation using TMT coupled with nano-LC-MS/MS

H Cao, X Zhu, X Chen, Y Yang, Q Zhou… - American Journal of …, 2020 - ncbi.nlm.nih.gov
Persistent atrial fibrillation (PeAF) is a progressive cardiovascular disease with a high risk for
most patients after diagnosis. Poor molecular description of PeAF has led to unsatisfactory …

Comprehensive metabolomic and proteomic analyses reveal candidate biomarkers and related metabolic networks in atrial fibrillation

J Zhou, L Sun, L Chen, S Liu, L Zhong, M Cui - Metabolomics, 2019 - Springer
… and proteomics analyses were performed to find candidate biomarkers. A targeted
quantification assay and an ELISA were performed to validate the results of the omics analyses. …

[HTML][HTML] A proteomic analysis of atrial fibrillation in a prospective longitudinal cohort (AGES-Reykjavik study)

T Jonmundsson, AE Steindorsdottir, TR Austin… - Europace, 2023 - academic.oup.com
Aims Atrial fibrillation (AF) is associated with high risk of comorbidities and mortality. Our
aim was to examine causal and predictive relationships between 4137 serum proteins and …

[HTML][HTML] Metabolomic and proteomic analyses of persistent valvular atrial fibrillation and non-valvular atrial fibrillation

B Hu, W Ge, Y Wang, X Zhang, T Li, H Cui… - Frontiers in …, 2021 - frontiersin.org
… Through metabolomic and proteomic analyses, we identified differential levels of proteins
and metabolites in non-valvular AF and valvular AF compared to SR samples, and found the …

[HTML][HTML] Integrative transcriptomic, proteomic, and machine learning approach to identifying feature genes of atrial fibrillation using atrial samples from patients with …

Y Liu, F Bai, Z Tang, N Liu, Q Liu - BMC Cardiovascular Disorders, 2021 - Springer
… To our knowledge, this is the first integrated transcriptomic and proteomic analysis of human
AF atrial tissue, and the first to identify feature genes of AF using machine learning approach…

[HTML][HTML] Label-free proteomic analysis of serum exosomes from paroxysmal atrial fibrillation patients

H Ni, W Pan, Q Jin, Y Xie, N Zhang, K Chen, T Lin… - Clinical Proteomics, 2021 - Springer
… either microRNAs or proteomic analysis of cardiac exosomes … proteomic analysis of bodily
fluids in AF is still unknown. In our study, we focus on the serum exosomes proteomic analysis

Comparative proteomic analysis of atrial appendages from rheumatic heart disease patients with sinus rhythm and atrial fibrillation

WJ Huang, R Zhou, XR Zeng… - Molecular …, 2011 - spandidos-publications.com
… In the present study, 2-DE-based proteomic analysis of human atrial tissue was carried
out to identify novel biomarkers for diagnosis and new targets for therapy. Differentially …

Substrate modifications precede the development of atrial fibrillation after cardiac surgery: a proteomic study

A Kourliouros, X Yin, A Didangelos, MT Hosseini… - The Annals of thoracic …, 2011 - Elsevier
… In this study we utilized modern proteomic techniques in the analysis of left atrial tissue of
patients in SR at baseline, and identified changes specifically associated with the development …