… This review aims to give a translational overview on the biological basis of atrial remodeling
and the proarrhythmic mechanisms involved in the fibrillation process. We pay attention to …

Atrial fibrillation (AF) is a very common cardiac arrhythmia with an estimated prevalence of
33.5 million patients globally. It is associated with an increased risk of death, stroke and …

… atrial-restricted targeting of specific molecular arrhythmia mechanisms; and (4) clarifying
the response of the substrate to interventions. For each of these, we describe the translational …

… A schematic representation of the history of atrial fibrillation (AF) research, leading to our
present understanding of clinically relevant mechanisms. ANS indicates autonomic nervous …

Background A growing body of evidence suggests that atrial fibrillation ( AF ) is associated
with myocardial infarction ( MI ). However, incidence and management of MI in AF is still …

… prepares neurologists to critically appraise these trials. … 8 of 94 patients with paroxysmal
atrial fibrillation, and a Danish … % of patients with paroxysmal atrial fibrillation and 5.1% of those …

Atrial fibrillation (AF), the most common sustained arrhythmia in clinical practice, is an
important contributor to cardiac morbidity and mortality. Pharmacological approaches currently …

… in our understanding of the complex mechanisms underlying atrial fibrillation (AF). The
epidemic of AF … There is urgency for effective translational programs in this field to facilitate more …

Successful translation of research focussing on atrial arrhythmogenic mechanisms has
potential to provide a mechanism-tailored classification and to support personalised treatment …

Atrial fibrillation (AF) is the most common sustained arrhythmia, and its prevalence in the
population is increasing. 1 Diastolic dysfunction shares many common risk factors with AF, …