… We evaluated the effect of osmotic-release oral system (OROS) methylphenidate on
learning skills in adolescents with attention-deficit/hyperactivity disorder (ADHD). In an open-label …

… Although the mechanism of action of osmotic release oral system-… , slow-release MPH, which
has a pharmacokinetic profile providing controlled MPH release by using osmotic pressure (…

… the chief complaint of attention deficit, hyperactivity, or … osmotic-release MPH treatment
at the same time of day (10.00–11.00 hours). ADHD subjects were treated with osmotic-release …

… compliance with osmotic-release oral system methylphenidate than with immediate-release …
from immediate-release methylphenidate to osmotic-release oral system methylphenidate …

… In this study, we investigated the effect of a long-acting form of methylphenidate, osmotic-release
oral system (OROS) methylphenidate, on multiple domains of attention, as well as …

… The development and regulatory approval of effective extended-release (ER) stimulant
preparations, such as osmotic, controlled-release (OROS) MPH, addresses many of these …

… had been osmotic-release methylphenidate because that was the only sustained-release …
the immediate release preparation, 4–8 so it was the stimulant drug of choice at that time. …

Attention-deficit/hyperactivity disorder (ADHD) is neurobehavioral disorder characterized by
inattention, hyperactivity/impulsivity and impaired reward system function, such as delay …

… of osmotic-release oral system (OROS)-methylphenidate (MPH) in adults (19-60 years of
age) with attention deficit/… of pharmacotherapy for adult attention-deficit/hyperactivity disorder. …

OBJECTIVE: To evaluate the efficacy and safety of osmotic-release methylphenidate (OROS-MPH)
compared with placebo for attention-deficit/hyperactivity disorder (ADHD), and the …