… basis, with at least another 40 additional diseases suspected. In contrast to the role of
endogenous cells in autoimmune disease, transplanted cells elicit an undesired immune response …

… However, these are the consequences of autoimmunity and, if we aspire to reinstate
immune tolerance, we need better biomarkers of ‘immune health’. Transplantation tolerance …

… to genetic factors can give rise to autoimmune disease. Progress in delineating these
opposing signals provides opportunities to correct the primary disorder in autoimmune patients. …

… be able to afford dominant tolerance provided they are properly activated … immune responses.
Here, we review nanoparticle-based approaches designed to induce immune tolerance, …

… The goal of ongoing research in immune tolerance is the development of autoantigen-… of
self-reactive immune-cell function, while maintaining the ability of the immune system to clear …

… of immune tolerance in inflammatory diseases is an area of intensive research. In this area,
HSPs are a target for tolerance-… In humans, in whom the actual disease trigger is frequently …

… Immune tolerance and autoimmunity are important clinically. Firstly, there are at least 40
known or suspected autoimmune diseases, and many are common (see box). Overall, 1 person …

… human B-cell tolerance may prove to be vital in the further exploration of underlying tolerance
defects. In this review, we supply a comprehensive overview of human immune tolerance …

… periphery, thereby preventing autoimmune disease. The majority, … organ-specific autoimmune
diseases in otherwise normal … self-tolerance and how autoimmune disease develops when …

… disease. In this review, we describe the phenomenon of immune tolerance and provide an
… understanding of the molecular mechanisms of immune tolerance can be used to develop …