Adoptive therapy with chimeric antigen receptor–modified T cells of defined subset composition

SR Riddell, D Sommermeyer, C Berger, LS Liu… - The Cancer …, 2014 - journals.lww.com
… including acute lymphoblastic leukemia, chronic lymphocytic leukemia, and lymphoma
have been induced into a complete remission after receiving an infusion of autologous T cells

Heterogeneity of human T4+ inducer T cells defined by a monoclonal antibody that delineates two functional subpopulations.

EL Reinherz, C Morimoto, KA Fitzgerald… - … (Baltimore, Md.: 1950 …, 1982 - journals.aai.org
T cells defined by anti-T4 and anti-T4, were reciprocal and nonoverlapping with the subset
of T cells defined … unfractionated T cells to soluble antigens and to autologous non-T cells in …

Specifically activated memory T cell subsets from cancer patients recognize and reject xenotransplanted autologous tumors

P Beckhove, M Feuerer, M Dolenc… - The Journal of …, 2004 - Am Soc Clin Investig
… In the present study, we separated naive and memory T cells from … autologous tumor
xenotransplants upon adoptive transfer with DCs. We demonstrate that only memory T cell subsets

Specific lymphocyte subsets predict response to adoptive cell therapy using expanded autologous tumor-infiltrating lymphocytes in metastatic melanoma patients

LG Radvanyi, C Bernatchez, M Zhang, PS Fox… - Clinical Cancer …, 2012 - AACR
… + T cells expressing BTLA (B- and T- lymphocyte attenuator) were highly associated with
clinical response. This cell subset may … We further analyzed the different subsets of T cells using …

Functional subsets of human monocytes defined by monoclonal antibodies: a distinct subset of monocytes contains the cells capable of inducing the autologous mixed …

HH Shen, MA Talle, G Goldstein… - Journal of immunology …, 1983 - journals.aai.org
… An alternative possibility is that only distinct subset(s) of T cells have the receptors … the
subset of T cells defined by the monoclonal antibody T-29 is capable of responding to autologous

Evolution of peripheral blood T lymphocyte subsets after allogenic or autologous hematopoietic stem cell transplantation

B Puissant-Lubrano, A Huynh, M Attal, A Blancher - Immunobiology, 2014 - Elsevier
… The naïve and memory T cell subsets were defined as follows: central memory T … allogenic
or autologous HSCT, we show that the rate and the nature of the T cell reconstitution is very …

Sorting through subsets: which T-cell populations mediate highly effective adoptive immunotherapy?

CA Klebanoff, L Gattinoni, NP Restifo - Journal of immunotherapy, 2012 - journals.lww.com
… infiltrating tumor deposits (or TIL) frequently possess specific reactivity against autologous
or HLA-matched tumor lines. When TIL are obtained from surgically resected tumor masses, …

Abstract CT131: a phase I study of adoptive immunotherapy for advanced ROR1+ malignancies with defined subsets of autologous T cells expressing a ROR1 …

…, S Srivastava, V Voillet, J Veatch, T Gooley… - Cancer Research, 2018 - AACR
CT131: A phase I study of adoptive immunotherapy for advanced ROR1+ malignancies with
defined subsets of autologous T cells expressing a ROR1-specific chimeric antigen receptor …

A randomized clinical trial of autologous T-cell therapy in multiple sclerosis: subset analysis and implications for trial design

E Fox, D Wynn, S Cohan, D Rill… - Multiple Sclerosis …, 2012 - journals.sagepub.com
… myelin reactive T-cells that maintain autoimmune processes within the CNS. Tovaxin® is
an autologous T-cell immunotherapy that consists of a pool of up to six T-cell lines raised …

Salvage chemotherapy and autologous stem cell transplantation for peripheral T-cell lymphoma: a subset analysis of the Canadian Cancer Trials Group LY. 12 …

T Skamene, M Crump, KJ Savage, T Reiman… - Leukemia & …, 2017 - Taylor & Francis
… this subset analysis, the findings are subject to bias arising from multiple testing [Citation37]. …
the largest described cohort in relapsed/refractory, transplant-eligible, peripheral T-cell