Post-transcriptional dynamics and RNA homeostasis in autophagy and cancer

SP Kolapalli, TM Nielsen, LB Frankel - Cell Death & Differentiation, 2023 - nature.com
… We additionally shed light on how autophagy can regulate RNA homeostasis, as well as
previously unrecognized roles for core autophagy machinery proteins as RNA binders. …

The autophagyRNA interplay: degradation and beyond

MH Abildgaard, SH Brynjólfsdóttir, LB Frankel - Trends in Biochemical …, 2020 - cell.com
… players in the secretion and intracellular transport of RNA and related … for RNA homeostasis
and gene expression programs, as well as their implications for disease, including cancer

Long noncoding RNAs act as regulators of autophagy in cancer

T Sun - Pharmacological research, 2018 - Elsevier
… of autophagy, a crucial cellular homeostatic mechanism that plays a pro-survival or pro-death
role in cancer. Deregulation of lncRNAs can contribute to tumorigenesis and cancer

Endothelial cell autophagy in homeostasis and cancer

J Verhoeven, J Baelen, M Agrawal, P Agostinis - FEBS letters, 2021 - Wiley Online Library
… In line with this, heightened EC autophagy is involved in pathological … by autophagy in
ECs under physiological conditions and discuss recent evidence implicating EC autophagy in …

Calcium homeostasis and ER stress in control of autophagy in cancer cells

E Kania, B Pająk, A Orzechowski - BioMed research …, 2015 - Wiley Online Library
… The major factors influencing autophagy are Ca 2+ homeostasis perturbation and starvation.
homeostasis and glucose deprivation in ER stress-mediated autophagy induction in cancer

Mechanisms and context underlying the role of autophagy in cancer metastasis

CM Dower, CA Wills, SM Frisch, HG Wang - Autophagy, 2018 - Taylor & Francis
autophagy an attractive target for cancer therapy. Emerging research indicates that autophagy
also influences cancer … Basal levels of autophagy maintain cellular homeostasis through …

Emerging connections between RNA and autophagy

LB Frankel, M Lubas, AH Lund - Autophagy, 2017 - Taylor & Francis
… types of RNA and RNA-related complexes are recruited to and degraded by the autophagy
… importance in the regulation of RNA homeostasis and translational and genomic control in …

Autophagy-modulating long non-coding RNAs (LncRNAs) and their molecular events in cancer

MZ Islam Khan, SY Tam, HKW Law - Frontiers in genetics, 2019 - frontiersin.org
… Some of them play key roles in drug resistance while some inhibit autophagy to maintain
homeostasis in cancer micro-environments. In the contrary, down-regulated lncRNAs induce/…

A circular RNA circ-DNMT1 enhances breast cancer progression by activating autophagy

WW Du, W Yang, X Li, FM Awan, Z Yang, L Fang, J Lyu… - Oncogene, 2018 - nature.com
… increased expression of a circular RNA circ-Dnmt1 in eight breast cancer cell lines and in …
cancer cells by stimulating cellular autophagy. We found that circ-Dnmt1-mediated autophagy

Autophagy-related long non-coding RNA signature for ovarian cancer

C Meng, JQ Zhou, YS Liao - Journal of International Medical …, 2020 - journals.sagepub.com
… novel cancer treatments. In this study, we used an online dataset to determine a new and …
autophagy-related lncRNA signature for OC prognosis. Our signature may affect the autophagy-…