Autophagy suppresses breast cancer metastasis by degrading NBR1

T Marsh, J Debnath - Autophagy, 2020 - Taylor & Francis
… and how autophagy stimulation affects cancer progression and therapy. … autophagy on
functional outcomes in breast cancer progression. We uncover a dichotomous role of autophagy

Autophagy‐related prognostic signature for breast cancer

Y Gu, P Li, F Peng, M Zhang, Y Zhang… - Molecular …, 2016 - Wiley Online Library
… , we found that autophagy genes were implicated in breast cancer. Then, … autophagy
prognostic signature for breast cancer in a training dataset. We identified a set of eight autophagy

The importance of autophagy regulation in breast cancer development and treatment

JM Zarzynska - BioMed research international, 2014 - Wiley Online Library
autophagy inhibitor. The miR-101-mediated inhibition of autophagy sensitized breast cancer
… 101 was suggested to modulate the chemosensitivity of cancer cells [29]. Three components…

Autophagy regulation in the development and treatment of breast cancer

Y Zhou, EB Rucker III, BP Zhou - Acta biochimica et biophysica …, 2016 - academic.oup.com
… components from the autophagic pathway [6]. This review provides an overview of the
interplay of autophagy with breast cancer metastasis and summarizes a list of autophagy-deficient …

FSIP1 regulates autophagy in breast cancer

C Liu, L Sun, J Yang, T Liu, Y Yang… - Proceedings of the …, 2018 - National Acad Sciences
… been identified as a poor prognostic indicator of breast cancer. Here, we report that FSIP1 …
breast cancer (TNBC) cells, and its silencing promotes drug resistance by inducing autophagy

Roles of autophagy in breast cancer treatment: Target, bystander or benefactor

L Tyutyunyk-Massey, DA Gewirtz - Seminars in cancer biology, 2020 - Elsevier
… [7], interference with therapy-induced autophagy could be counterproductive. In this review
we will focus on autophagy induced in breast cancer by conventional treatments and its …

PPARγ activation induces autophagy in breast cancer cells

J Zhou, W Zhang, B Liang, MC Casimiro… - The international journal …, 2009 - Elsevier
… of double-membrane autophagic vacuoles by electron … To determine the mechanism by
which PPARγ induces autophagy, we … of autophagy by PPARγ activation in breast cancer cells …

Autophagy supports breast cancer stem cell maintenance by regulating IL6 secretion

P Maycotte, KL Jones, ML Goodall, J Thorburn… - Molecular cancer …, 2015 - AACR
… growth delay when autophagy is inhibited in … autophagy dependency with two different
breast cancer cell lines: MCF7 and MDA-MB-468. The former being independent of autophagy

STAT3-mediated autophagy dependence identifies subtypes of breast cancer where autophagy inhibition can be efficacious

P Maycotte, CM Gearheart, R Barnard, S Aryal… - Cancer research, 2014 - AACR
cancer cells behave the same way when autophagy is inhibited. We inhibited autophagy in
a panel of breast cancer cell lines and found that some of them are dependent on autophagy

[HTML][HTML] The pro-apoptotic role of autophagy in breast cancer

S Suman, TP Das, R Reddy, AM Nyakeriga… - … journal of cancer, 2014 - nature.com
… is a catabolic process that has a vital role in cancer … target autophagy, result in growth
inhibition in many cancer types. In this study, we examined the role of autophagy in breast cancer (…