The role of autophagy in cancer development and response to therapy

Y Kondo, T Kanzawa, R Sawaya, S Kondo - Nature Reviews Cancer, 2005 - nature.com
… suppresses tumorigenesis or provides cancer cells with a rescue mechanism under … role
of autophagy in cancer development, and in response to therapy? And how can the autophagic

Selective autophagy in cancer development and therapy

I Dikic, T Johansen, V Kirkin - Cancer research, 2010 - AACR
… Recently, autophagy has been connected to cancer development and progression: (1) it …
in autophagy can lead to tumor development (2). The controversial view on autophagy as a cell …

The dynamic nature of autophagy in cancer

AC Kimmelman - Genes & development, 2011 - genesdev.cshlp.org
autophagy therapies as an entirely new approach to cancer treatment. It is now apparent that
aberrant control of autophagy is among the key hallmarks of cancer… functions of autophagy, …

The dual role of autophagy in cancer development and a therapeutic strategy for cancer by targeting autophagy

CW Yun, J Jeon, G Go, JH Lee, SH Lee - International journal of …, 2020 - mdpi.com
… In this review, we summarize several mechanisms of autophagy in cancer biology as …
autophagy in cancer stem cells (CSCs). Finally, we discuss the potential of targeting autophagy

The role for autophagy in cancer

E White - The Journal of clinical investigation, 2015 - Am Soc Clin Investig
… which to address the role of autophagy in cancer. Given the tissue-specific, homeostatic
function of autophagy, addressing the role of autophagy in cancer in physiologic settings, such …

Molecular mechanisms of autophagy in cancer development, progression, and therapy

VAM Vitto, S Bianchin, AA Zolondick, G Pellielo… - Biomedicines, 2022 - mdpi.com
… , its activation induces lethal effects on cancer cells. In this review, … of autophagy and its
dual role in cancer. In addition, we report the current understanding of autophagy in some cancer

Autophagy and cancer

KS Choi - Experimental & molecular medicine, 2012 - nature.com
… regulation of autophagy in cancer, it appears to provide a promising target for cancer treatment.
… Future studies will be needed to clarify whether the induction of autophagic cancer cell …

[HTML][HTML] Ras and autophagy in cancer development and therapy

E Schmukler, Y Kloog, R Pinkas-Kramarski - Oncotarget, 2014 - ncbi.nlm.nih.gov
… In conclusion, Ras and autophagy may have dual effect on cancer progression depending
on … when designing novel anti-cancer therapeutics based on Ras and autophagy modulation. …

[HTML][HTML] Autophagy in cancer

X Zhi, Q Zhong - F1000prime reports, 2015 - ncbi.nlm.nih.gov
… , autophagy is a key cell survival mechanism for established tumors; therefore autophagy
Here, we summarize recent progress on the role of autophagy in tumorigenesis and cancer

[HTML][HTML] Autophagy regulation in cancer development and therapy

EJ White, V Martin, JL Liu, SR Klein, S Piya… - … journal of cancer …, 2011 - ncbi.nlm.nih.gov
… genes in cancer. We discuss the relevance of autophagy in cancer development and
progression, and the potential role of autophagy in cancer therapy. …