… Given the role of autophagy in facilitating tumor growth, autophagy inhibition has gained …
of autophagy in cancer, as well as the prospects of autophagy inhibition for cancer therapy. Clin …

… autophagic response. In this review we provide an overview of the signalling pathways that
influence autophagy, particularly in cancer … pathways can have significant effects on cancer …

… of autophagy and its dual role in cancer. In addition, we report the current understanding of
autophagy in some cancer … Therefore, it is essential to identify which molecular pathways are …

… Early findings indicated a dual role of autophagy in cancer, and ongoing studies are …
autophagy influences cancer initiation and progression 7 . It is now widely accepted that autophagy …

… differ depending on the tumor stage, cell type and/or genetic factors, and we need to
determine how specific pathways of autophagy are activated or inhibited by the various anti-…

… molecular pathways of autophagy, both tumor suppressive and oncogenic functions of
autophagy … and complicated, first and foremost because autophagy is a highly context-dependent …

… of autophagy in cancer appears to change during tumor progression. Autophagy protects …
, when presumably autophagy has been suppressed, restoration of autophagy promotes tumor …

… in cancer may affect the autophagy pathway to enable cancer cells to adapt and survive under
low oxygen conditions via the stress response signaling pathway, … of autophagy in cancer …

… These two features of the molecular pathways of autophagy implicate that we may be able
… manipulating autophagy to kill cancer cells effectively. The pathways of autophagy activated …

… Here we review the two-faced role of autophagy in cancer as a tumor suppressor or as a
pro… pathways that play a role in autophagy and malignant transformation. Finally, anti-cancer …