Combination of an autophagy inducer and an autophagy inhibitor: a smarter strategy emerging in cancer therapy

T Liu, J Zhang, K Li, L Deng, H Wang - Frontiers in pharmacology, 2020 - frontiersin.org
autophagy combined with autophagy inhibitors. … autophagy as a cancer therapeutic approach
in clinical application. Thus, we need to facilitate the exploitation of appropriate autophagy

Natural compounds from herbs that can potentially execute as autophagy inducers for cancer therapy

SR Lin, YS Fu, MJ Tsai, H Cheng, CF Weng - International Journal of …, 2017 - mdpi.com
… Hereby, the underlying mechanisms of natural autophagy inducers are … for autophagy
inducers that can trigger cell death in a supplement or alternative medicine for cancer therapy. …

Autophagy inducers in cancer

M Russo, GL Russo - Biochemical pharmacology, 2018 - Elsevier
… of the involvement of autophagy in cancer therapy. They agree that the inhibition of … studies
in cancer prevention or therapy based on the treatment with the potential autophagy inducers

Autophagy and cancer therapy

P Maycotte, A Thorburn - Cancer biology & therapy, 2011 - Taylor & Francis
… both using autophagy inhibitors or inducers together with other cancer treatments underscores
… some of the recent work studying the role of autophagy with different cancer therapies. …

Challenges and therapeutic opportunities of autophagy in cancer therapy

VR Silva, SP Neves, LS Santos, RB Dias, DP Bezerra - Cancers, 2020 - mdpi.com
… of the autophagy inducers that can cause cancer cell death, … autophagy inducers should
be carried out to increase knowledge about the action potential of these drugs in cancer therapy

Autophagy and cancer therapy

Y Kondo, S Kondo - Autophagy, 2006 - Taylor & Francis
… The topoisomerase II inhibitor etoposide, a known apoptosis inducer, induces autophagic
cell death in Bax/Bak-/- mouse embryonic fibroblasts (MEFs).Etoposide-induced cell death is …

Autophagy and cancer therapy

A Thorburn, DH Thamm, DL Gustafson - Molecular pharmacology, 2014 - ASPET
… Both these canonical apoptosis inducers are relevant for cancer therapy. TRAIL receptor
agonists are being tested as anticancer agents (Dimberg et al., 2013), and although FasL …

Autophagy modulation for cancer therapy

ZJ Yang, CE Chee, S Huang… - … biology & therapy, 2011 - Taylor & Francis
therapeutic strategy. Studies are ongoing to define optimal strategies to modulate autophagy
for cancer prevention and therapy, … that transactivates several autophagy inducers including …

Development of autophagy inducers in clinical medicine

B Levine, M Packer, P Codogno - The Journal of clinical …, 2015 - Am Soc Clin Investig
… designed to be more selective inducers of autophagy function in target organs … autophagy
inducers in medicine, the factors to be considered in defining disease targets for such therapy

The role of autophagy in cancer: therapeutic implications

ZJ Yang, CE Chee, S Huang, FA Sinicrope - Molecular cancer therapeutics, 2011 - AACR
autophagy may represent a major impediment to successful cancer therapy, and thus, it
represents a novel therapeutic … are autophagy inducers, IRE1 negatively regulates autophagy. …