Role of CYB5A in pancreatic cancer prognosis and autophagy modulation
E Giovannetti, Q Wang, A Avan, N Funel… - … the National Cancer …, 2014 - academic.oup.com
… To shed light on the molecular events driving autophagy, we evaluated 84 genes encoding
key components of the autophagic machinery. The volcano plot in Figure 3A arranged the …
key components of the autophagic machinery. The volcano plot in Figure 3A arranged the …
Therapeutic modulation of autophagy: which disease comes first?
MC Maiuri, G Kroemer - Cell Death & Differentiation, 2019 - nature.com
… , and drugs that favor autophagy. In this review, we discuss the role of autophagy in disease
… will become the first clinically approved indication for therapeutic autophagy modulation. …
… will become the first clinically approved indication for therapeutic autophagy modulation. …
[HTML][HTML] Role and regulation of autophagy in cancer
N Chen, V Karantza-Wadsworth - … et Biophysica Acta (BBA)-Molecular Cell …, 2009 - Elsevier
… The impact of Ras activation on the functional status of autophagy in tumors has not yet
been determined. Also, whether autophagy modulation by Ras plays any role in the …
been determined. Also, whether autophagy modulation by Ras plays any role in the …
Molecular insights into therapeutic potential of autophagy modulation by natural products for cancer stem cells
… autophagy modulation and CSCs control using natural products. Overall, we emphasize the
importance of understanding the role of autophagy … strategies for cancer treatment targeting …
importance of understanding the role of autophagy … strategies for cancer treatment targeting …
Autophagy-modulating long non-coding RNAs (LncRNAs) and their molecular events in cancer
MZ Islam Khan, SY Tam, HKW Law - Frontiers in genetics, 2019 - frontiersin.org
… autophagy-modulating lncRNAs autophagy in cancers, their … and physiological roles of
autophagy-modulating lncRNAs in … on the extent of autophagy at different carcinogenic stages, …
autophagy-modulating lncRNAs in … on the extent of autophagy at different carcinogenic stages, …
The dual role of autophagy in cancer
EL Eskelinen - Current opinion in pharmacology, 2011 - Elsevier
… Moreover, the antiapoptotic proteins Bcl-2 and Bcl-XL inhibit autophagy by blocking the …
, but also by inhibiting autophagy. Several other autophagy modulating proteins also have …
, but also by inhibiting autophagy. Several other autophagy modulating proteins also have …
Autophagy and autophagy-related pathways in cancer
… Basal differentiation has been implicated in aggressive, pro-metastatic phenotypes in
breast cancer 74 , yet how autophagy modulates these subpopulations during the metastatic …
breast cancer 74 , yet how autophagy modulates these subpopulations during the metastatic …
The role of autophagy in cancer: therapeutic implications
ZJ Yang, CE Chee, S Huang, FA Sinicrope - Molecular cancer therapeutics, 2011 - AACR
… for evaluating autophagy modulation during therapy and correlating such modulation with
… Biomarkers to measure autophagy modulation during treatment should be an important …
… Biomarkers to measure autophagy modulation during treatment should be an important …
Therapeutic potential of autophagy modulation in cholangiocarcinoma
H Perez-Montoyo - Cells, 2020 - mdpi.com
… ], and how autophagy modulation shows anticancer efficacy in preclinical models. This
review collects clinical and preclinical scientific reports involving autophagy modulation in CCA, …
review collects clinical and preclinical scientific reports involving autophagy modulation in CCA, …
Targeting autophagy for cancer treatment and tumor chemosensitization
M Pérez-Hernández, A Arias, D Martínez-García… - Cancers, 2019 - mdpi.com
… understanding of autophagy regulation and … autophagy modulation in cancer. In this review,
the molecular mechanisms that regulate autophagy and the dual role of autophagy in cancer …
the molecular mechanisms that regulate autophagy and the dual role of autophagy in cancer …