[HTML][HTML] Activation of autophagy pathway suppresses the expression of iNOS, IL6 and cell death of LPS-stimulated microglia cells

HE Han, TK Kim, HJ Son, WJ Park… - Biomolecules & …, 2013 - ncbi.nlm.nih.gov
microglia, though details of the mechanism remain largely unknown. In the present study, we
… the role of the autophagy pathway in activated BV2 microglia cells. In BV2 cells, rapamycin …

Canonical and noncanonical autophagy pathways in microglia

J Jülg, L Strohm, C Behrends - Molecular and cellular biology, 2021 - Taylor & Francis
… components by canonical autophagy, recently identified noncanonical pathways participate
in … on the molecular aspects of both autophagy pathway variants in microglia. MICROGLIA

The role of autophagy in modulation of neuroinflammation in microglia

P Su, J Zhang, D Wang, F Zhao, Z Cao, M Aschner… - Neuroscience, 2016 - Elsevier
… Recent advances also reveal a crucial role of autophagic pathway and proteins in immunity
… , suggesting that activation of microglial cells with PGN might induce autophagy and …

The role of autophagy in pro‐inflammatory responses of microglia activation via mitochondrial reactive oxygen species in vitro

J Ye, Z Jiang, X Chen, M Liu, J Li… - Journal of …, 2017 - Wiley Online Library
… ) and autophagy pathway might be involved in microglial … , we regulated autophagy pathway
of microglia in vitro by autophagymicroglial BV-2 cells or cultured primary mouse microglial

Autophagy and microglia: novel partners in neurodegeneration and aging

A Plaza-Zabala, V Sierra-Torre, A Sierra - International journal of …, 2017 - mdpi.com
… on macroautophagy, since it is the autophagic pathway that has mainly been connected to
… Therefore, we believe that during the next decade autophagy research in microglial cells

Autophagy promotes microglia activation through Beclin-1-Atg5 pathway in intracerebral hemorrhage

B Yuan, H Shen, L Lin, T Su, L Zhong, Z Yang - Molecular neurobiology, 2017 - Springer
… 2b), suggesting that erythrocyte lysis promotes cellular autophagic flux. To further confirm that
… The beclin-1-Atg5 is the classical autophagy pathway. We assessed the effects of Beclin1 …

A critical role of autophagy in regulating microglia polarization in neurodegeneration

M Jin, F Wang, DI Qi, W Liu, C Gu, CJ Mao… - Frontiers in Aging …, 2018 - frontiersin.org
… -α inhibits autophagy in microglia through AKT/mTOR signaling pathway, and autophagy
and observed the changes of polarization markers in TNF-α-challenged microglia cells. The …

Beclin1‐driven autophagy modulates the inflammatory response of microglia via NLRP 3

J Houtman, K Freitag, N Gimber, J Schmoranzer… - The EMBO …, 2019 - embopress.org
… of primary mouse microglia or the microglial cell line BV2 after knockdown of autophagy
genes (… BECN1 is a key protein of the autophagic pathway, and its reduction in Becn1 +/− mice …

Role of microglia autophagy in microglia activation after traumatic brain injury

Y Jin, R Wang, S Yang, X Zhang, J Dai - World Neurosurgery, 2017 - Elsevier
… of the autophagy inhibitor 3-methyladenine (3-MA) on microgliamicroglia activation and
microglia autophagy. Inhibition of … autophagy inhibitor 3-MA inhibited autophagic cell death of …

The role of the P2X7 receptor signaling pathway for the release of autolysosomes in microglial cells

T Takenouchi, M Fujita, S Sugama, H Kitani… - Autophagy, 2009 - Taylor & Francis
pathway in inflammation and neurodegeneration, this noncanonical autophagic pathway
Recently, the role of autophagy in the innate immune system has been well recognized. For …