Antihyperalgesic and side effects of intrathecal clonidine and tizanidine in a rat model of neuropathic pain

T Kawamata, K Omote, H Yamamoto… - The Journal of the …, 2003 - pubs.asahq.org
… Intrathecal drug administration was accomplished using a microinjection syringe (Hamilton,
Reno, NV) connected to the intrathecal catheter in awake, briefly restrained rats. Intrathecal …

Picrotoxin produces a “central” pain-like syndrome when microinjected into the somato-motor cortex of the rat

JL OLIVERAS, J MONTAGNE-CLAVEL - Physiology & behavior, 1996 - Elsevier
Rat RECENTLY, we reported that it is possible to produce a “pain-like” behavior in the awake
rat… ,” perhaps such as cramping that is reported by patients in association with muscular

[HTML][HTML] Thoracic 9 spinal transection-induced model of muscle spasticity in the rat: a systematic electrophysiological and histopathological characterization

JA Corleto, M Bravo-Hernández, K Kamizato… - PLoS …, 2015 - journals.plos.org
… in gastrocnemius muscle in fully awake restrained rats [29]. Using this system coupled with
rat … presented as chronic pain and/or general spinally-mediated hyperexcitability including …

Awake behaving electrophysiological correlates of forelimb hyperreflexia, weakness and disrupted muscular synchronization following cervical spinal cord injury in …

PD Ganzer, EC Meyers, AM Sloan, R Maliakkal… - Behavioural brain …, 2016 - Elsevier
Awake behaving electrophysiological recordings of muscle function across multiple … In
the current study, we assessed muscular dysfunction following unilateral cSCI using awake

Muscle pain, myofascial pain, and fibromyalgia: recent advances

L Vecchiet, MA Giamberardino - 1999 - books.google.com
… likely to determine the degree of spontaneous pain in an awake individual. [Article copies …
In anesthetised rats, the gastrocnemius-soleus [GS] muscle was inflamed by injecting it with …

Characterization of incisional and inflammatory pain in rats using functional tools of MRI

S Amirmohseni, D Segelcke, S Reichl, L Wachsmuth… - Neuroimage, 2016 - Elsevier
… sensitized skin and muscle afferent fibers, … pain related activation patterns in awake rats.
However, the similarities between BOLD results in our study and those reported for awake rats

Persistent deep mechanical hyperalgesia induced by repeated cold stress in rats

T Nasu, T Taguchi, K Mizumura - European Journal of Pain, 2010 - Elsevier
… of muscle nociception in awake animals easier, and will promote the study of muscle pain.
The present experiment also showed that RCS at 4 C induced prolonged muscle mechanical …

Fatiguing exercise enhances hyperalgesia to muscle inflammation

KA Sluka, LA Rasmussen - Pain, 2010 - Elsevier
pain and many people with chronic pain present with fatigue, we tested if fatigue would enhance
the response to pain … Carrageenan (0.03%) was injected into the gastrocnemius muscle

[HTML][HTML] Further validation of a model of fibromyalgia syndrome in the rat

PG Green, P Alvarez, RW Gear, D Mendoza… - … Journal of Pain, 2011 - Elsevier
… in awake rats. Three days prior to nociceptive assessment, … of muscle pain (vis-à-vis overlying
skin pain). The nociceptive threshold was defined as the force, in Newtons, at which the rat

Remote astrocytic and microglial activation modulates neuronal hyperexcitability and below-level neuropathic pain after spinal injury in rat

YS Gwak, CE Hulsebosch - Neuroscience, 2009 - Elsevier
Muscle and fascia were sutured and skin closed with autoclips, and … rats are nocturnal
animals, the animals were housed in a reverse day/night cycle and tested during their “awake” …