… by culture on agar plates containing axenic medium. We used these to explore whether effects
of axenic culture … Our results imply that major nutrient components of axenic medium, and …

… We conclude that growth in axenic culture is marked by a … genes are down-regulated in axenic
culture [21]. In an attempt … metabolism caused by growth in axenic culture, but our findings …

… FF is fully fed, ADRl is axenic dietary restriction in liquid medium, ADRs is axenic dietary
restriction on solid medium. The graphs show the average results of at least 2 biological …

… In conclusion, axenic medium has a large effect on life span, … coli dilution, eat-mutation or
axenic culture are very similar. … similar DR effect on life span as restricting energetic content. …

… medium lengthens life span by a number of mechanisms, including food restriction.
Hence we denote the food restriction action of axenic medium axenic dietary restriction (ADR). …

… We assume that axenic culture medium elicits a DR response, without causing starvation.
However, we cannot rule out special life enhancing mechanisms underlying ADR. …

… axenic dietary restriction–induced longevity. Here, we provide solid evidence that axenic
dietary restriction … induction is not required for axenic dietary restriction–mediated longevity. We …

… Abstract: Dietary restriction (DR) delays the onset of age-related deterioration and extends
… We report that food restriction imposed by axenic culture reduces the exponential increase of …

… culture conditions, consistent with nutrient deprivation seen in other DR regimens. A DR
effect of axenic culture is also suggested by the observation that worms grown in axenic medium …

… coli are not nearly as long-lived as in axenic culture, and are fully fertile (unlike in axenic
culture). Thus, freedom from the harmful effects of bacteria cannot fully account for the effects of …