Evidence for galanin receptors in primary sensory neurones and effect of axotomy and inflammation
… In the present study we demonstrate that the first cloned galanin receptor, GAL-R1, is expressed
in at least 1/5 of all DRG neurones and that these neurones also express CGRP mRNA. …
in at least 1/5 of all DRG neurones and that these neurones also express CGRP mRNA. …
Expression and regulation of galanin-R2 receptors in rat primary sensory neurons: effect of axotomy and inflammation
… Using in situ hybridization, we studied galanin-R2 receptor (… tissue inflammation and sciatic
nerve transection (axotomy). … profiles after peripheral tissue inflammation with a peak at 3 …
nerve transection (axotomy). … profiles after peripheral tissue inflammation with a peak at 3 …
Central and peripheral expression of galanin in response to inflammation
RR Ji, X Zhang, Q Zhang, Å Dagerlind, S Nilsson… - Neuroscience, 1995 - Elsevier
… and their processes, and also that galanin released from primary afferents reacts mainly
with post-junctional galanin receptors. Since axotomy produces a marked plasticity in neuro…
with post-junctional galanin receptors. Since axotomy produces a marked plasticity in neuro…
A new gal in town: a systematic review of the role of galanin and its receptors in experimental pain
D Fonseca-Rodrigues, A Almeida, F Pinto-Ribeiro - Cells, 2022 - mdpi.com
… Additionally, after axotomy of the sciatic nerve, blocking galanin action by the administration
… anti-inflammatory role for this receptor. After inflammation or nerve injury, galanin receptors …
… anti-inflammatory role for this receptor. After inflammation or nerve injury, galanin receptors …
Regulation of expression of galanin and galanin receptors in dorsal root ganglia and spinal cord after axotomy and inflammation.
… galanin-R2 receptor mRNA levels increase. The present results show that galanin and galanin
receptors … local dorsal horn neurons and are regulated by nerve injury and inflammation. …
receptors … local dorsal horn neurons and are regulated by nerve injury and inflammation. …
Galanin in Somatosensory Function a
Z WIESENFELD‐HALLIN… - Annals of the New York …, 1998 - Wiley Online Library
… the galanin R1 receptor found in normal DRG cells in rat was transiently downregulated during
inflammation, 10 whereas the R2 galanin receptor … that following axotomy galanin may be …
inflammation, 10 whereas the R2 galanin receptor … that following axotomy galanin may be …
Differential distribution and regulation of galanin receptors-1 and-2 in the rat lumbar spinal cord
P Brumovsky, F Mennicken, D O'donnell, T Hökfelt - Brain research, 2006 - Elsevier
… The expression of the galanin receptor-1 and -2 (Gal 1 and … unilateral axotomy of the sciatic
nerve or unilateral inflammation … In this study, crushing or axotomy of the facial nerve induced …
nerve or unilateral inflammation … In this study, crushing or axotomy of the facial nerve induced …
Inflammation-and axotomy-induced changes in galanin-like immunoreactive (GAL-LI) nerve structures in the porcine descending colon
S Gonkowski, P Burliński, C Skobowiat… - Acta Veterinaria …, 2010 - akjournals.com
… This study reports on changes caused by chemically driven inflammation and axotomy in
galanin-… Both colitis and axotomy caused an increase in GALlike immunoreactivity, which was …
galanin-… Both colitis and axotomy caused an increase in GALlike immunoreactivity, which was …
The participation of galanin in pain processing at the spinal level
… is regulated by nerve injury and peripheral inflammation. The functional significance of such
… distinctly changed by axotomy because GAL1 receptor and GAL2 receptor mRNA levels are …
… distinctly changed by axotomy because GAL1 receptor and GAL2 receptor mRNA levels are …
The role of galanin as a multi-functional neuropeptide in the nervous system
D Wynick, SWN Thompson, SB McMahon - Current opinion in …, 2001 - Elsevier
… After axotomy, galanin mRNA and peptide are abundantly expressed in 40–50% of all DRG
… a dual role for galanin as a central, spinal mediator of inflammatory pain hypersensitivity and …
… a dual role for galanin as a central, spinal mediator of inflammatory pain hypersensitivity and …
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