Scopoletin stimulates melanogenesis via cAMP/PKA pathway and partially p38 activation

DS Kim, SB Cha, MC Park, SA Park, HS Kim… - Biological and …, 2017 - jstage.jst.go.jp
cells. Here, we found that scopoletin-induced melanogenesis occurs via the cAMP/PKA
signaling pathway and partially p38 MAPK … synthesis of B16 mouse melanoma cells by 1 alpha, …

Inhibition of the p38 and PKA signaling pathways is associated with the anti-melanogenic activity of Qian-wang-hong-bai-san, a Chinese herbal formula, in B16 cells

TF Tsang, Y Ye, WCS Tai, GX Chou, AKM Leung… - Journal of …, 2012 - Elsevier
… In summary, the TCM formula QW was able to inhibit tyrosinase activity and melanin content
in B16 cells through, at least in part, inhibiting the p38 MAPK and PKA signaling pathways. …

Silibinin promotes melanogenesis through the PKA and p38 MAPK signaling pathways in melanoma cells

T Uto, T Ohta, K Katayama, Y Shoyama - Biomedical Research, 2022 - jstage.jst.go.jp
… in murine B16-F1 and human HMV-II melanoma cells. Silibinin … A (PKA), and p38
mitogen-activated protein kinase (MAPK) but … The specific PKA (H-89) and p38 (SB203580) …

A novel psoralen derivative-MPFC enhances melanogenesis via activation of p38 MAPK and PKA signaling pathways in B16 cells

L Yin, G Pang, C Niu, M Habasi… - … journal of molecular …, 2018 - spandidos-publications.com
… of MPFC-stimulated B16 mouse melanoma cells. Our results … MPFC increased the
phosphorylation of p38 mitogen-activated … of the p38 MAPK and the protein kinase A (PKA) …

Role of p38 MAPK in lupeol-induced B16 2F2 mouse melanoma cell differentiation

K Hata, K Hori, S Takahashi - Journal of biochemistry, 2003 - academic.oup.com
… of p38 MAPK in B16 2F2 cells. SB203580, a selective inhibitor of … that the p38 MAPK pathway
was involved in lupeol-induced B16 2F2 cell differentiation as a downstream target of PKA. …

Inhibitory effect of dried pomegranate concentration powder on melanogenesis in B16F10 melanoma cells; involvement of p38 and PKA signaling pathways

SJ Kang, BR Choi, EK Lee, SH Kim, HY Yi… - International journal of …, 2015 - mdpi.com
… of the p38 MAPK pathway in B16F10 cells. PCP reduced the phosphorylation of p38 MAPK,
but not ERK … of PKA, CREB, and GSK-β compared with α-MSH alone. This indicates that the …

Tobramycin promotes melanogenesis by upregulating p38 MAPK protein phosphorylation in B16F10 melanoma cells

SH Moon, YC Chung, CG Hyun - Antibiotics, 2019 - mdpi.com
… We identified the effects of tobramycin on the cAMP/PKA, MAPK, and PI3K/AKT signaling
pathways, which are important pathways for melanogenesis, using Western blot experiments …

Ssanghwa-tang, an oriental herbal cocktail, exerts anti-melanogenic activity by suppression of the p38 MAPK and PKA signaling pathways in B16F10 cells

A Kim, NH Yim, M Im, YP Jung, C Liang… - … and Alternative Medicine, 2013 - Springer
… SHT efficiently inhibited c-AMP-induced melanin synthesis in B16F10 cells via suppression
of PKA and p38 MAPK signaling pathways and subsequently decreased the level of CREB …

Liquiritin and liquiritigenin induce melanogenesis via enhancement of p38 and PKA signaling pathways

T Uto, T Ohta, A Yamashita, S Fujii, Y Shoyama - Medicines, 2019 - mdpi.com
… melanocyte cells, the mitogen-activated protein kinase (MAPK) family, including p38 MAPK
(p38) … In addition, we measured the cytotoxicity of LQ and LQG in B16-F1 cells using the MTT …

Enhancement of the p38 MAPK and PKA signaling pathways is associated with the pro-melanogenic activity of Interleukin 33 in primary melanocytes

J Zhou, J Song, F Ping, J Shang - Journal of dermatological science, 2014 - Elsevier
… rhIL-33 activated p38 MAPK and PKA pathways through up-… , a specific inhibitor of p38 MAPK,
and H89, an inhibitor of PKA on … physiological functions of cells. Besides the direct effect of …