Bacillus Calmette–Guérin immunotherapy for cancer

F Cardillo, M Bonfim, P da Silva Vasconcelos Sousa… - Vaccines, 2021 - mdpi.com
… Therefore, based on these results, we can observe a promising role of BCG in cancer. BCG
induces type I IFN and results in signaling and APC activation. This inflammatory axis could …

Contemporary outcomes of patients with nonmuscle-invasive bladder cancer treated with bacillus Calmette-Guérin: implications for clinical trial design

JT Matulay, R Li, PJ Hensley, NA Brooks… - The Journal of …, 2021 - auajournals.org
… receiving adequate bacillus Calmette-Guérin therapy at a tertiary cancer center between …
-free survival—muscle-invasive bladder cancer and overall survival were used to create …

Bacillus Calmette-Guérin strain differences have an impact on clinical outcome in bladder cancer immunotherapy

CA Rentsch, FD Birkhäuser, C Biot, JR Gsponer… - European urology, 2014 - Elsevier
Background Whether the commonly used bacillus Calmette-Guérin (BCG) strains Connaught
and Tice confer different treatment responses in non–muscle-invasive bladder cancer (…

Building on a solid foundation: enhancing bacillus Calmette-Guerin therapy

CA Rentsch, L Derré, SG Dugas, C Wetterauer… - European urology …, 2018 - Elsevier
Bacillus Calmette-Guérin (BCG) immunotherapy to prevent the recurrence and progression
… strains are undergoing clinical trial testing to improve outcomes for bladder cancer patients. …

… Bladder Cancer Group consensus statement on clinical trial design for patients with bacillus Calmette-Guérin–exposed high-risk non–muscle-invasive bladder cancer

M Roumiguié, AM Kamat, TJ Bivalacqua, SP Lerner… - European urology, 2022 - Elsevier
… Our consensus provides a precise definition of the disease state for bladder cancer not
invading the bladder muscle and exposed to bacillus Calmette-Guérin (BCG) treatment. Clear …

Impact of bacillus Calmette–Guérin therapy of upper urinary tract carcinoma in situ: comparison of oncological outcomes with radical nephroureterectomy

H Horiguchi, T Yoneyama, S Hatakeyama, N Tokui… - Medical Oncology, 2018 - Springer
… of nephron-sparing therapy, bacillus Calmette–Guérin (BCG) … Here, we compared oncological
outcomes and safety … in terms of toxicity and oncological outcomes. Our result showed that …

… bacillus Calmette-Guerin reduces the risk of progression in patients with superficial bladder cancer: a meta-analysis of the published results of randomized clinical …

RJ Sylvester, APM van der MEIJDEN… - The Journal of …, 2002 - auajournals.org
… We determine if intravesical bacillus Calmette-Guerin (BCG) reduces the risk of progression
after … or higher in patients with superficial (stage Ta, T1 or carcinoma in situ) bladder cancer. …

The role of bacillus Calmette-Guérin in the treatment of non–muscle-invasive bladder cancer

P Gontero, A Bohle, PU Malmstrom, MA O'Donnell… - European urology, 2010 - Elsevier
… After more than 30 yr of research, bacillus Calmette-Guérin (BCG) remains the most effective
intravesical treatment in non–muscle-invasive bladder cancer (NMIBC). The key element of …

Randomized controlled study of the efficacy, safety and quality of life with low dose bacillus Calmette-Guérin instillation therapy for nonmuscle invasive bladder cancer

A Yokomizo, Y Kanimoto, T Okamura, S Ozono… - Journal of …, 2016 - journals.lww.com
cancer is controversial. We investigated if induction therapy with low dose bacillus Calmette-…
to that of standard dose bacillus Calmette-Guérin, with less toxicity and higher quality of life. …

Clinical and preclinical therapies for bladder cancer following bacillus Calmette-Guérin failure

M Nazmifar, C Williams, A Naser-Tavakolian… - Journal of …, 2023 - journals.lww.com
… invasive bladder cancer after previous intravesical bacillus Calmette-Guérin. Bacillus Calmette-…
failed 1 or more courses of prior bacillus Calmette-Guérin therapy were included. Studies …