Baculovirus vectors for gene therapy

YC Hu - Advances in virus research, 2006 - Elsevier
… area, cells permissive to baculovirus transduction, factors … gene therapy, as well as
advantages, limitations, and safety issues concerning use of baculoviruses as gene therapy vectors. …

Baculovirus as a tool for gene delivery and gene therapy

C Ono, T Okamoto, T Abe, Y Matsuura - Viruses, 2018 - mdpi.com
… Here, we summarize the application of baculovirus as a gene expression vector and the …
by baculovirus in mammalian cells. We also discuss the future prospects of baculovirus vectors. …

Baculoviral vectors for gene delivery: a review

YC Hu - Current gene therapy, 2008 - ingentaconnect.com
… These pioneering studies pave the way to utilizing baculoviral vector for gene delivery into …
robust and noninvasive baculoviral vector MRI [64]. The same baculovirus can also be coated …

The baculovirus expression vector system: A commercial manufacturing platform for viral vaccines and gene therapy vectors

RS Felberbaum - Biotechnology journal, 2015 - Wiley Online Library
… of viral vaccines and gene therapy vectors. Nine BEVS‐… next generation vaccines, vectors
for gene therapy, and other … developments in the gene therapy and influenza vaccine fields …

Baculoviruses in gene therapy and personalized medicine

S Schaly, M Ghebretatios, S Prakash - … : Targets and Therapy, 2021 - Taylor & Francis
… Limitations such as transient gene expression, … further genetic modifications and other
methods. This review concludes that baculoviruses are an excllent candidate for gene therapy, …

Baculovirus as mammalian cell expression vector for gene therapy: an emerging strategy

S Ghosh, MK Parvez, K Banerjee, SK Sarin… - Molecular Therapy, 2002 - cell.com
The monopoly of insect cells to host baculovirus Autographa californica multiple nuclear
polyhedrosis virus (AcMNPV) as a eukaryotic gene expression system has been shattered with …

Manufacturing of AcMNPV baculovirus vectors to enable gene therapy trials

TW Kwang, X Zeng, S Wang - Molecular therapy Methods & clinical …, 2016 - cell.com
… potential of baculovirus as a delivery vector for a variety of therapeutic applications … in
using baculoviruses as human gene therapy vectors, which has led to advances in baculovirus

Baculovirus vectors for antiangiogenesis-based cancer gene therapy

WY Luo, YS Shih, WH Lo, HR Chen, SC Wang… - … gene therapy, 2011 - nature.com
… of baculovirus vector for antiangiogenic cancer gene therapy, we constructed Bac-hEA which
harbored the hEA fusion genetherapeutic protein expression is desired for cancer therapy

Baculovirus vectors: novel mammalian cell gene-delivery vehicles and their applications

A Hüser, C Hofmann - American Journal of Pharmacogenomics, 2003 - Springer
gene expression cassette into a baculovirus vector, we could show that the envelope-modified
vector is able to deliver a reporter gene … other viral vectors for gene delivery/gene therapy

Efficient gene transfer into human hepatocytes by baculovirus vectors.

C Hofmann, V Sandig, G Jennings… - Proceedings of the …, 1995 - National Acad Sciences
vector for liver-directed gene therapy. If compared with the existing tools for gene transfer to
hepatocytes, recombinant baculovirus … and retroviral vectors regarding the efficiency of gene