… serum levels of BAFF and BAFF/APRIL correlate with treatment … to identify active forms of
BAFF and APRIL in the circulation, … for dual BAFF/APRIL inhibition versus single BAFF inhibition …

… is a vital B-cell survival factor and overexpression of BAFF in both mice and humans is
associated with systemic lupus erythematosus (SLE). The anti-BAFF monoclonal antibody (mAb), …

… the aim of correlating changes of BAFF and APRIL levels to the absence/presence of circulating
B cells, we chose to study serum levels of BAFF and APRIL in the patients with SLE at B-…

… This review describes the function of BAFF and its homolog APRIL (a proliferation-inducing
ligand) and addresses the rationale for the treatment of SLE with BAFF/APRIL inhibitors. …

… BAFF (2). Recently, we showed that in (NZB × NZW)F 1 mice, a murine model of lupus, the
expression of BAFF and APRIL … Whether B cells express BAFF and APRIL in human SLE has …

… Circulating levels of BAFF, APRIL and membrane-bound BAFF, increase in response to Toll-…
BAFF and APRIL have been found to be elevated both in humans with SLE and lupus-prone …

… (TNF) family ligands BAFF (B-cell activating factor of TNF family) and APRIL (a proliferation-…
of BAFF and APRIL have been reported earlier in patients with systemic lupus erythematosus …

… In this context, the aims of this work were to associate the costimulatory effect of BAFF and
APRIL through BAFF-R and TACI on CD3+ T cells and the cytokine serum profiles in SLE …

… serum BAFF or APRIL and changes in SLEDAI-2k, or between baseline serum BAFF or APRIL
and … However, between-visit changes in BAFF were significantly different in patients with …

… Systemic lupus erythematosus (SLE) is the prototype of an … BAFF, is the only biologic approved
for SLE and active lupus … Many studies reported elevated soluble BAFF and APRIL levels …