Evolution of energy metabolism, stem cells and cancer stem cells: how the Warburg and Barker hypothesis might be linked

JE Trosko - BMC proceedings, 2013 - Springer
… in the stem cell field, where “induced pluripotent stem cells”(“iPS”… cells, namely, they were
selected adult stem cells in those primary cultures [9]. In addition, the isolation of “MUSE” cells

The gap junction as a “Biological Rosetta Stone”: implications of evolution, stem cells to homeostatic regulation of health and disease in the Barker hypothesis

JE Trosko - Journal of cell communication and signaling, 2011 - Springer
… adult stem cells, Warburg metabolism and cancer stem cells supports the stem cell hypothesis
of the origin of cancer and the adult stem cells as the target cell for the “cancer stem cell”. …

Adult Stem Cells, the Barker Hypothesis, Epigenetic Events, and Low-Level Radiation Effects

JE Trosko, K Suzuki - Radiation Health Risk Sciences: Proceedings of the …, 2009 - Springer
… of adult stem cells during prenatal and early postnatal development, that is, the Barker
hypothesis [… In addition, the isolation of adult human stem cells and their ability to be neoplastically …

Adult Stem Cells, the Barker Hypothesis, Epigenetic Events, and Low-Level

JE Troskol, K Suzuki - … Health Risk Sciences: Proceedings of the …, 2009 - books.google.com
… be a classic example of the Barker hypothesis [26]. More recently, it has been shown that
there is a correlation of umbilical cord blood hematopoietic stem cells with birth weight and its …

Tracking down the stem cells of the intestine: strategies to identify adult stem cells

N Barker, H Clevers - Gastroenterology, 2007 - gastrojournal.org
… Neither of these 2 hypotheses on stem cell identity is supported by direct definitive
evidence for stemness along the lines discussed in the first paragraph. For such evidence, the …

Epigenetic modifications at the center of the barker hypothesis and their transgenerational implications

RJ Ryznar, L Phibbs, LJ Van Winkle - International journal of …, 2021 - mdpi.com
stem cell technologies. Researchers are currently working on ambitious efforts to convert adult
stem cells … we are able to produce gamete cells from stem cells. Jamie Metzel, in the book …

The intestinal stem cell

N Barker, M Van De Wetering… - Genes & …, 2008 - genesdev.cshlp.org
… accessible models for the study of adult stem cell biology. This review attempts to provide a
comprehensive overview of four decades of research on crypt stem cells. … zone” hypothesis. …

[PDF][PDF] The Barker Hypothesis

F Page - 1924 - researchgate.net
cells is copied in all daughter cells at mitosis to direct the growth and specific functions of an
organ. The body might retain stem cells … tissues with more than one cell type if needed, but …

The fascinating theory of fetal programming of adult diseases: A review of the fundamentals of the Barker hypothesis

G Faa, V Fanos, M Manchia… - Journal of Public …, 2024 - journals.sagepub.com
… Here, we provide a narrative summary of the most relevant evidence supporting the Barker
hypothesis in multiple fields of medicine, including neuropsychiatric disorders, such as …

[PDF][PDF] Fetal programming of atherosclerosis: may the barker hypothesis explain the susceptibility of a subset of patients to develop stroke or cardiac infarct?

C Gerosa, G Faa, D Fanni, G Cerrone… - European Review for …, 2021 - europeanreview.org
… The Barker’s hypothesis was based on epidemiological data … Over the years, the Barker’s
hypothesis has been confirmed … Renal endogenous stem cells: a new source for regenerative …