Adenosine receptor–dopamine receptor interactions in the basal ganglia and their relevance for brain function

K Fuxe, S Ferré, S Genedani, R Franco, LF Agnati - Physiology & behavior, 2007 - Elsevier
receptors are major receptors in the regulation of striatal function and striatal adenosine A 1
and A 2A receptors … –D 1 heteromeric receptor complexes in the basal ganglia and prefrontal …

Adenosine–dopamine receptorreceptor interactions as an integrative mechanism in the basal ganglia

S Ferré, K Fuxe, BB Fredholm, M Morelli… - Trends in neurosciences, 1997 - cell.com
… specific subtypes of adenosine and dopamine receptors in the basal ganglia are involved in
… effects of adenosine receptor agonists and the motor stimulant effects of adenosine receptor

Adenosine A2A receptors and basal ganglia physiology

SN Schiffmann, G Fisone, R Moresco, RA Cunha… - Progress in …, 2007 - Elsevier
ganglia system. They are predominantly expressed in enkephalin-expressing GABAergic …
of the basal ganglia system. In these GABAergic enkephalinergic neurons, the A 2A receptor

Adenosine A2 receptors: selective localization in the human basal ganglia and alterations with disease

MI Martinez-Mir, A Probst, JM Palacios - Neuroscience, 1991 - Elsevier
… , the target for neuroleptics, to enkephalinergic cells in the rat striatumJ 3 The data
presented in this report are consistent with the localization of A2 adenosine receptors on …

New Aspects of Physiological and Pathophysiological Functions of Adenosine A2A Receptor in Basal Ganglia

H Kase - Bioscience, biotechnology, and biochemistry, 2001 - Taylor & Francis
… for the various adenosine receptors have increased our understanding of the function of
adenosine and its receptors. Four different subtypes of adenosine receptors are now identified …

The role of extracellular adenosine in chemical neurotransmission in the hippocampus and Basal Ganglia: pharmacological and clinical aspects

B Sperlágh, E Sylvester Vizi - Current topics in medicinal …, 2011 - ingentaconnect.com
… the basal ganglia circuits producing akinesia, bradykinesia, tremor, and rigidity [126]…
Adenosine exerts its effects in the basal ganglia by acting through A1 and A2A adenosine receptors

Adenosine A2a receptor expression in striatal neurons: Implications for basal ganglia pathophysiology

SN Schiffmann, P Halleux, R Menu… - Drug development …, 1993 - Wiley Online Library
… in basal ganglia physiology and pathophysiology. The drug development of new adenosine
receptor … widen the therapeutical arsenal in basal ganglia degenerative diseases such as in …

Blocking striatal adenosine A2A receptors: a new strategy for basal ganglia disorders

CE Muller, S Ferré - Recent Patents on CNS Drug Discovery …, 2007 - ingentaconnect.com
… the basal ganglia. … adenosine receptors predominantly of the A2A and D2 subtype,
respectively, while GABAergic dynorphinergic neurons express dopamine and adenosine receptors

… detection of A1 adenosine receptors in rat brain with emphasis on localization in the hippocampal formation, cerebral cortex, cerebellum, and basal ganglia

SA Rivkees, SL Price, FC Zhou - Brain research, 1995 - Elsevier
… for A1 receptors. Immunohistochemistry of CHO cells transfected with the rat or human A 1
adenosine receptor cDNAs showed … We did not observe labeling of fibers in the basal ganglia. …

Indirect basal ganglia pathway mediation of repetitive behavior: attenuation by adenosine receptor agonists

Y Tanimura, S Vaziri, MH Lewis - Behavioural brain research, 2010 - Elsevier
… To investigate further the role of the indirect basal ganglia pathway, we examined neuronal
… Co-administration of the adenosine A 2A receptor agonist CGS21680 and the A 1 receptor