[HTML][HTML] Methods and applications of CRISPR-mediated base editing in eukaryotic genomes
… to repair and re-write genomes, recently developed base-editing systems present a useful
orthogonal strategy to engineer nucleotide substitutions. Base editing relies on recruitment of …
orthogonal strategy to engineer nucleotide substitutions. Base editing relies on recruitment of …
DNA base editing in nuclear and organellar genomes
… The availability of protein-only genome editing reagents … the extension of base editing to
the genomes of chloroplasts … base editing methods for nuclear and organellar genomes. We …
the genomes of chloroplasts … base editing methods for nuclear and organellar genomes. We …
Precise A· T to G· C base editing in the rice genome
… applications of CRISPR-mediated base editing in eukaryotic genomes. … base editors in
rice, which greatly broaden the genome engineering toolkit for plants. The adenine base editors …
rice, which greatly broaden the genome engineering toolkit for plants. The adenine base editors …
Microbial base editing: a powerful emerging technology for microbial genome engineering
… known as base editing, opened new avenues for microbial genome engineering. Base editing
… Here, we review ongoing efforts to develop and apply base editing to engineer industrially …
… Here, we review ongoing efforts to develop and apply base editing to engineer industrially …
CRISPR-mediated base editing enables efficient disruption of eukaryotic genes through induction of STOP codons
… -mediated base editing for gene disruption studies. We show that CRISPR base editors
efficiently … Notably, 94%–99% of genes in the analyzed eukaryotic genomes can be targeted with …
efficiently … Notably, 94%–99% of genes in the analyzed eukaryotic genomes can be targeted with …
Precise plant genome editing using base editors and prime editors
… This Review focuses on base editing and prime editing platforms that enable single-…
genomes. We first present a comprehensive overview of the available and forthcoming base editing …
genomes. We first present a comprehensive overview of the available and forthcoming base editing …
Base editing: precision chemistry on the genome and transcriptome of living cells
… Base editing is a newer genome-editing approach that uses … DNA base editors comprise
a catalytically disabled nuclease … RNA base editors achieve analogous changes using …
a catalytically disabled nuclease … RNA base editors achieve analogous changes using …
Base editing: advances and therapeutic opportunities
EM Porto, AC Komor, IM Slaymaker… - Nature Reviews Drug …, 2020 - nature.com
… base editing provides the means for irreversible, permanent changes to the genome, RNA
base editing … Chronologically, RNA base editing predates both DNA base editing and the use …
base editing … Chronologically, RNA base editing predates both DNA base editing and the use …
CRISPR base editors: genome editing without double-stranded breaks
A Eid, S Alshareef, MM Mahfouz - Biochemical Journal, 2018 - portlandpress.com
… for genome editing applications across eukaryotic species, but major drawbacks, such as the
inefficiency of precise base editing … , including base editing, to specific DNA sequences. As …
inefficiency of precise base editing … , including base editing, to specific DNA sequences. As …
Progress in the application of CRISPR: from gene to base editing
W Wu, Y Yang, H Lei - Medicinal Research Reviews, 2019 - Wiley Online Library
… this system has been developed into an efficient tool to edit eukaryotic genomes and
revolutionized the field of genome engineering, such as creating complex animal models of human-…
revolutionized the field of genome engineering, such as creating complex animal models of human-…
相关搜索
- cytosine base editing precision genome engineering
- genome and transcriptome base editing
- nuclear genomes base editing
- rice genome base editing
- microbial genome engineering base editing
- eukaryotic genes base editing
- targeted a-to g base editing
- base editing scope
- crispr cas mediated base editing
- base editing in corynebacterium glutamicum
- highly efficient base editing
- physcomitrium physcomitrella patens base editing
- crispr tool kit base editing
- plant science base editing
- therapeutic opportunities base editing
- dna specificity base editing