… RNA base editors achieve analogous changes using components that target RNA. Base editors
directly convert one base or base pair … editing by-products. In this Review, we summarize …

… in editing efficiency. Finally, we show that an adenine base editor 7 can also induce
transcriptome-wide RNA edits… These results have implications for the use of base editors in both …

… system in tomato, we investigated the potential genome-wide off-target effects of this promising
base editor. We conducted WGS on four edited T0 lines (two independent lines each for …

… protein (Cas)-mediated base editing tools (eg, ABEs and cytosine base editors), which
efficiently produce desired point mutations in genomic DNA without causing double-stranded …

… ), which has been exploited for more precise base editing, and the resulting eA3A-BE3 base
editor exhibited high on-target precision with minimized bystander editing (18). However, in …

… In this Perspective, we discuss the various base editing tools available for direct chemical
modification of target nucleobases in the genome and transcriptome and their potential for …

… deaminases leads to base editors (BEs) capable of programmable C-to-T editing, which has
… induces efficient editing with only background levels of genome-wide and transcriptome-…

… process of genome and transcriptome editing (Figs 1 and 2). Both DNA and RNA base
editors have been developed, and their rapid adoption by the genome and transcriptome editing …

… This Review focuses on base editing and prime editing … and a combination thereof in plant
genomes. We first present a … modification of genomes (DNA) or transcriptomes (RNA) of …

… Having identified ABE8e as an efficient and pure base editor in tomato, we focused on
investigating ABE8e's potential genome-wide off-target effects. WGS was carried out on 2 WT …