… base editors achieve analogous changes using components that target RNA. Base editors
directly convert one base or base … -dividing cells without generating excess undesired editing …

… in living cells — is one of the most recent advances in the field of genome … cells process
base editing intermediates may additionally inform new therapeutic strategies using base editors…

… in living cells. Recently, CRISPR-free, protein-only base editors, such as double-stranded
DNA … toxin A-derived cytosine base editors (DdCBEs) and adenine base editors (ABEs), have …

… Live cell images were acquired using a Nikon Eclipse Ti inverted microscope. Image
acquisition was performed at room temperature and air in a 24-well plate. Sickled …

… With dozens of base editors now reported, it is … of base editors, each with its own unique
properties and potential uses. In this perspective, we describe currently available base editors, …

… Adenine base editors (ABEs) convert targeted A•T base pairs to G•C in living cells without
requiring DSBs or donor DNA templates, and with minimal formation of indels 2 . In SCD, the …

The originally published article contained errors in reference numbering throughout table 1 (DNA
base editors and their approximate editing windows) due to the unintended …

… Development of a specific cytosine base editing reporter: Cy GO To detect cytosine BE
events in real time in living cells, we sought to create a reporter that would become activated …

… was triggered through Me 2 Tz addition and the editing efficiency was computed as the C:…
base editing activities of BaseBAC over a 48 h time-course. We observed distinct C-to-T editing …

… Base editing induces single-nucleotide changes in the DNA of living cells using a fusion
protein containing a catalytically defective Streptococcus pyogenes Cas9, a cytidine deaminase…