… editing by-products. In this Review, we summarize base-editing strategies to generate specific
and precise … scope, specificity, precision and in vivo delivery of base editors and discuss …

… -nucleotide alterations in a precise and efficient manner is base editing. Base editing is unique
in … in the process of genome and transcriptome editing (Figs 1 and 2). Both DNA and RNA …

The originally published article contained errors in reference numbering throughout table 1 (DNA
base editors and their approximate editing windows) due to the unintended …

… –Crick base-pairing rules. A great advantage for the basic engineering of A-to-I base editing
is the … A-to-I editing effectors are usually composed of the DD of an ADAR enzyme, a target-…

… information about the DNA base editors that have been developed … to minimize or mitigate
those issues of DNA base editors. … scope and precision of base editing with engineered Cas9-…

… 1c), suggesting it is possible to innovate pure CBE, C-to-G base editors or dual-base editors
… a base editor with a refined editing window is challenging, especially editing a specific base …

… Base editing represents a new dimension of CRISPR/Cas-mediated precise editing to
generate single-nucleotide changes in DNA or RNA independently of double-strand breaks and …

… base editing tools, which include cytosine base editors (CBEs) and adenine base editors
(ABEs), are capable of inducing precise base … Thus, base editors have been widely used in a …

… , offering a generalizable solution for temporally controlling precision genome editing. … , our
goal was to generate a controllable base editing system. We therefore next aimed to leverage …

… precise modification of genes, but have yet to be used at a genome-scale throughput. Here,
we test the ability of the Target-AID base editor … context of base editing. Our results show that …