… base editors and discusses therapeutically relevant advances in the development of these
technologies. Emerging therapeutic opportunities and associated challenges are discussed. …

… -based and (ii) base editing approaches. Conceptually, … is base editing [37,38]. Consequently,
in this work, we focused on recent advancements in the field of mitochondrial base editing, …

… of genome editing technology, novel editing tools such as base editing and prime …
University proposed base editing (BE) in 2016. Base editing converts one target DNA base into …

… are highly efficient on-targeting deoxyribonucleic acid (DNA) editors. Here, we describe a …
in base editing technologies and current techniques for delivery of cell and gene therapies to …

… We have also explored the potential challenges faced by base editing … of base editing
technology. In conclusion, this article not only underscores the present state of base editing …

… There are two main DNA base editors developed to date enabling the conversion of all
four DNA base pairs: Cytosine base editors (CBE) and Adenine base editors (ABE) [5]. …

… and recode any base in a target transcript. In contrast to DNA base editing, analogous
changes … effects that appeal to various therapeutic applications. The current practice of RNA …

… This review focuses on recent articles that have employed base editors (BEs) for both … base
editing strategies withclinical applications in cancer immunotherapy and gene therapy, which …

… editing in animal research studies. Both cytosine and adenine base editors have been applied
successfully to the editing of … Similarly, both base editors have achieved precise editing of …

… SpCas9 orthologs, and developing prime editing technology. In this review, … base editing,
focusing on its targeting scope, and we provide a workflow for selecting a suitable base editor …