Current status and challenges of DNA base editing tools
… DNA base editor shortcomings, including off-target DNA editing, … , which arise from the main
DNA base editor constituents, a Cas … information about the DNA base editors that have been …
DNA base editor constituents, a Cas … information about the DNA base editors that have been …
Web-based design and analysis tools for CRISPR base editing
… two web tools for base editors, named BE-Designer and BE-Analyzer. BE-Designer provides
all possible base editor … BE-Analyzer, a tool for assessing base editing outcomes from next …
all possible base editor … BE-Analyzer, a tool for assessing base editing outcomes from next …
Base editing: advances and therapeutic opportunities
EM Porto, AC Komor, IM Slaymaker… - Nature Reviews Drug …, 2020 - nature.com
… provides the means for irreversible, permanent changes to the genome, RNA base editing
… base editing predates both DNA base editing and the use of CRISPR for genome editing …
… base editing predates both DNA base editing and the use of CRISPR for genome editing …
A review on advanced CRISPR-based genome-editing tools: base editing and prime editing
A Saber Sichani, M Ranjbar, M Baneshi… - Molecular …, 2023 - Springer
… On this account, additional research is needed to better refine base editing despite an …
genome-editing systems and the recently introduced Base editor, new base-editing systems have …
genome-editing systems and the recently introduced Base editor, new base-editing systems have …
BE-PLUS: a new base editing tool with broadened editing window and enhanced fidelity
… used to perform base editing. However, the narrow editing window of BE limits its utility. Here,
we developed a new editing technology named as base editor for programming larger C to …
we developed a new editing technology named as base editor for programming larger C to …
[HTML][HTML] Base editing in plants: current status and challenges
SS Bharat, S Li, J Li, L Yan, L Xia - The Crop Journal, 2020 - Elsevier
… base editing, RNA base editing offers a promising tool for precise RNA modification at the
RNA level. REPAIR (RNA editing … ), as the first generation of RNA base-editing technology, is …
RNA level. REPAIR (RNA editing … ), as the first generation of RNA base-editing technology, is …
Plant base editing and prime editing: the current status and future perspectives
J Li, C Zhang, Y He, S Li, L Yan, Y Li… - Journal of Integrative …, 2023 - Wiley Online Library
… Since the development of the first generation of base editor (BE) and prime editor (PE) for
base editing and prime editing in mammalian cells (Komor et al., 2016; Nishida et al., 2016; …
base editing and prime editing in mammalian cells (Komor et al., 2016; Nishida et al., 2016; …
Base editing and prime editing in laboratory animals
F Caso, B Davies - Laboratory animals, 2022 - journals.sagepub.com
… Similarly, both base editors have achieved precise editing of point mutations in somatic cells…
optimising these tools, base editing can address only a subset of possible base conversions …
optimising these tools, base editing can address only a subset of possible base conversions …
Exploring C-to-G and A-to-Y base editing in rice by using new vector tools
D Zeng, Z Zheng, Y Liu, T Liu, T Li, J Liu, Q Luo… - International Journal of …, 2022 - mdpi.com
… the editing performance of CGBEs in rice, explored the possibility of A-to-Y editing, and
developed a new ABE8e-EndoV tool, … for improving and enriching base editing tools in plants. …
developed a new ABE8e-EndoV tool, … for improving and enriching base editing tools in plants. …
Base editing in crops: current advances, limitations and future implications
… Genome-editing-based single-base changes could generate elite trait variants in crop …
genome-editing technologies, base editing has emerged as a novel and efficient genome-editing …
genome-editing technologies, base editing has emerged as a novel and efficient genome-editing …