… between the DNA methylomes of two human cell types, revealing the highly dynamic nature
of this epigenetic modification. The genomic context of the DNA methylation is resolved, …

… enabled investigators to profile genome methylation patterns at single-base resolution.
Remarkably, more than 20 eukaryotic methylomes have been generated thus far, with a majority …

… of DNA methylation, collectively referred to as whole-genome bisulfite sequencing (WGBS).
Single-base resolution DNA methylomes are … for the detection of cytosine DNA methylation [ …

… However, base-resolution iPSCs DNA methylomes are not yet available. Several studies
have shown that methylation profiles of iPSCs are aberrant with respect to those of embryonic …

… ) are commonly used for base resolution DNA methylome research. Although multiple tools
… compares the pros and cons of each in methylome profiling. We then discuss approaches to …

… to generate base-resolution methylomes. Furthermore, we provide a brief guideline for
base-… These strategies will be useful to perform large-scale, genome-wide DNA methylation …

… We envision that an atlas of single-base-resolution methylomes in different cell types will
help elucidate demethylase specificity mechanisms and identify new forms of epitranscriptomics…

… To examine the rice genomic methylation landscape and assess its functional significance,
we generated single-base resolution DNA methylome maps for Asian cultivated rice Oryza …

… -base nucleotide measurement of DNA methylation and accordingly the generation of
genome-… high-resolution DNA methylome. The comprehensive integration of DNA methylomes in …

… samples, and will facilitate the investigation of CTC DNA methylome. Second, this method is
… the CTC DNA methylome at single base resolution, which can discover a unique “CTC DNA …