… the results of the QXDx BCR-ABL %IS ddPCR assay and the ipsogen BCR-ABL1 Mbcr IS-…
) real-time quantitative PCR assay (r=0.996). In conclusion, the QXDx BCR-ABL %IS ddPCR …

… This study intended to establish a droplet digital PCR (dd-PCR) for monitoring minimal
residual disease (MRD) in patients with BCR/ABL (P210)-positive chronic myeloid leukemia (CML…

… digital PCR (ddPCR) technology to reliably measure M-BCR status and the presence of
BCR-ABL… When applied to cell-line models of CML, the assay accurately quantifies BCR-ABL …

… quantify BCR–ABL1 transcript levels. Furthermore, we did not find differences between
duplicate or quadruplicate analysis in terms of BCR–ABL1% IS values. Droplet digital PCR could …

… of interest-p210 BCR-ABL1, molecular … BCR-ABL1, as well as to consider the possible
future application of a more sophisticated method such as digital polymerase chain reaction…

… to reliably quantify low levels of residual BCR-ABL1 in patients in deep … of digital PCR (dPCR)
as a promising alternative for response monitoring in CML. dPCR offers an absolute BCR-…

… Digital PCR is characterized by a high degree of sensitivity and precision 1 that make it
particularly suitable for detection of BCR-ABL … for BCR-ABL/ABL with that of real-time PCR using …

… Digital PCR (dPCR) generates an absolute read out that is largely tolerant to variations in PCR
… for standardisation like the conversion of the BCR-ABL/ABL ratio to international scale (IS)…

… PCR product revealed a fusion between exon e6 of the BCR gene and exon a2 of the
ABL1 gene, resulting in an e6a2 BCR… -up by digital droplet polymerase chain reaction (ddPCR) …

… Reverse-transcription digital PCR (RT-dPCR) is an adaptation of this method that could
provide the robust and standardized workflow needed for truly standardized patient stratification. …